Tetralogy of Fallot for Life

Tetralogy of Fallot for Life Tetralogy of Fallot for Life (TOF LIFE) is an international, multi-centre observational research study. Tetralogy of Fallot, or TOF, is one of the most common congenital heart conditions and accounts for 7-10% of all congenital heart defects.

Around the world, 4 out of every 10,000 babies will be diagnosed with TOF. Currently, close to 40,000 babies are affected per year. Most babies born with this condition would require a heart operation to repair these defects. TOF is a life-long condition and patients often require follow-up even after the operation to monitor for any complications. Many variations of the repair operation are pract

Around the world, 4 out of every 10,000 babies will be diagnosed with TOF. Currently, close to 40,000 babies are affected per year. Most babies born with this condition would require a heart operation to repair these defects. TOF is a life-long condition and patients often require follow-up even after the operation to monitor for any complications. Many variations of the repair operation are pract

Tetralogy of Fallot for Life's cover photo
12/10/2015

Tetralogy of Fallot for Life's cover photo

The Team and SickKids ...SickKids Hospital in Toronto has been one of the world's leading centers in cardiac care since ...
11/26/2015

The Team and SickKids ...
SickKids Hospital in Toronto has been one of the world's leading centers in cardiac care since the 1930's. Over 600 index cardiac procedures take place annually. The team is led by Dr. Glen Van Arsdell, who performs up to 40 TOF repairs per year. The majority of SickKids patients underdo primary repair with a focus towards preserving the annulus.
SickKids was the first site to start recruitment for TOF-LIFE, with the first participant joining the study on June 10, 2015.

TOF-LIFE Has Started!The TOF-LIFE is a prospective, global, observational inception cohort study that investigates the i...
11/26/2015

TOF-LIFE Has Started!
The TOF-LIFE is a prospective, global, observational inception cohort study that investigates the impact of Tetralogy of Fallot surgical repair on heart health. We are excited to have our first site (SickKids in Toronto, Ontario), along with Royal Children's Hospital In Australia, West China Hospital in China and Manmohan Cardiothorasic Vascular & Transplant Center in Nepal up and running with more sites ready to start!

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