Updates in Cardiology and Beyond

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๐Ÿ”ด Abnormal Q Waves: Ischemic and Non-Ischemic Causes
19/09/2026

๐Ÿ”ด Abnormal Q Waves: Ischemic and Non-Ischemic Causes

๐Ÿ‡ช๐Ÿ‡บ EU Parliament Backs Stronger Action to Prevent Heart Diseaseโค๏ธ CVD causes 1.7 million deaths every year in the EU, wi...
19/09/2026

๐Ÿ‡ช๐Ÿ‡บ EU Parliament Backs Stronger Action to Prevent Heart Disease

โค๏ธ CVD causes 1.7 million deaths every year in the EU, with around 80% considered preventable.

๐Ÿ›ก๏ธ The EU is shifting from treating heart disease after it develops toward preventing it earlier.

๐Ÿšญ Measures target major risks including tobacco/nicotine, alcohol, unhealthy diets and physical inactivity.

๐Ÿฅ— The plan supports clearer food labels and action on ultra-processed foods.

๐Ÿฉบ More heart-health screening is encouraged, especially for people at higher risk.

Sourceแฆ https://www.europarl.europa.eu/news/en/press-room/20260911IPR47455/meps-want-better-prevention-of-cardiovascular-diseases-in-the-eu

Europeโ€™s biggest silent killer claims 1.7 million lives each year. The Safe Hearts Plan is the EUโ€™s first cardiovascular health strategy, and Parliament wants prevention to be at the heart of it.๐Ÿซ€๐Ÿค
Find out more in the first comment.

๐Ÿ”ด Pulmonary Acceleration Time ( )โœ… A shorter PAT (
19/09/2026

๐Ÿ”ด Pulmonary Acceleration Time ( )

โœ… A shorter PAT (

 #๐‘๐ข๐ฏ๐š๐ซ๐จ๐ฑ๐š๐›๐š๐ง ๐Ÿ.๐Ÿ“ ๐ฆ๐  ๐“๐ฐ๐ข๐œ๐ž ๐ƒ๐š๐ข๐ฅ๐ฒ: ๐•๐š๐ฌ๐œ๐ฎ๐ฅ๐š๐ซ-๐๐ซ๐จ๐ญ๐ž๐œ๐ญ๐ข๐จ๐ง ๐ƒ๐จ๐ฌ๐žRivaroxaban 2.5 mg twice daily, when combined with low-dose as...
06/09/2026

#๐‘๐ข๐ฏ๐š๐ซ๐จ๐ฑ๐š๐›๐š๐ง ๐Ÿ.๐Ÿ“ ๐ฆ๐  ๐“๐ฐ๐ข๐œ๐ž ๐ƒ๐š๐ข๐ฅ๐ฒ: ๐•๐š๐ฌ๐œ๐ฎ๐ฅ๐š๐ซ-๐๐ซ๐จ๐ญ๐ž๐œ๐ญ๐ข๐จ๐ง ๐ƒ๐จ๐ฌ๐ž

Rivaroxaban 2.5 mg twice daily, when combined with low-dose aspirin (75โ€“100 mg once daily), is a vascular-protection regimen used in selected patients with:

โ€”๐‚๐ก๐ซ๐จ๐ง๐ข๐œ ๐œ๐จ๐ซ๐จ๐ง๐š๐ซ๐ฒ ๐ฌ๐ฒ๐ง๐๐ซ๐จ๐ฆ๐ž (๐‚๐‚๐’/๐‚๐€๐ƒ)
โ€”๐’๐ฒ๐ฆ๐ฉ๐ญ๐จ๐ฆ๐š๐ญ๐ข๐œ ๐ฉ๐ž๐ซ๐ข๐ฉ๐ก๐ž๐ซ๐š๐ฅ ๐š๐ซ๐ญ๐ž๐ซ๐ฒ ๐๐ข๐ฌ๐ž๐š๐ฌ๐ž (๐๐€๐ƒ/)
โ€”๐๐€๐ƒ ๐Ÿ๐จ๐ฅ๐ฅ๐จ๐ฐ๐ข๐ง๐  ๐ฅ๐จ๐ฐ๐ž๐ซ-๐ž๐ฑ๐ญ๐ซ๐ž๐ฆ๐ข๐ญ๐ฒ ๐ซ๐ž๐ฏ๐š๐ฌ๐œ๐ฎ๐ฅ๐š๐ซ๐ข๐ณ๐š๐ญ๐ข๐จ๐ง

This strategy is often referred to as dual-pathway inhibition, combining low-dose factor Xa inhibition with antiplatelet therapy to reduce major cardiovascular and limb events.

The 2.5 mg twice-daily dose is not a full therapeutic anticoagulant dose and should not be used as the anticoagulant regimen for:

Atrial fibrillation โ†’ stroke/systemic embolism prevention requires the appropriate AF anticoagulant dose.

Acute DVT or PE โ†’ treatment requires the full therapeutic VTE regimen.

๐Ÿ”ด   Study: Aute Heart Failure in Africa (Lancet, 2026)Aetiology, Management, and Outcomes of Aute Heart Failure across 1...
05/09/2026

๐Ÿ”ด Study: Aute Heart Failure in Africa (Lancet, 2026)

Aetiology, Management, and Outcomes of Aute Heart Failure across 17 African Countries: A Prospective, Multicentre, Observational Cohort Study

โ€ข 50 hospitals across 17 African countries
โ€ข 1,578 pts with acute HF
โ€ข Enrolment period: July 2024 โ€“ July 2025
โ€ข Follow-up: 180 days
โ€ข 17 Participating Countries: Angola, Botswana, Cameroon, Democratic Republic of Congo, , Ghana, Mauritania, Mozambique, Namibia, Nigeria, Sรฃo Tomรฉ and Prรญncipe, South Africa, Sudan, Tanzania, Tunisia, Uganda, Zambia.

Demographic Data

โ€ข Median age: 56 years (IQR 40โ€“69)
โ€ข Female: 50.5%
โ€ข African descent: 97.8%

Cardiovascular Risk Factors & Comorbidities

โ€ข Hypertension: 62.7%
โ€ข Diabetes: 20.3%
โ€ข Dyslipidaemia: 15.8%
โ€ข HIV-positive: 3.4%

Leading Aetiologies of AHF

1. Hypertensive heart disease: 36.5%
2. Cardiomyopathy: 23.4%
3. Ischaemic heart disease: 23.3%
4. Other causes: 6.8%

Clinical Presentation โ€” Median (IQR)

โ€ข BMI: 23.7 kg/mยฒ (21.2โ€“27.4)
โ€ข Systolic BP: 124 mmHg (107โ€“142)
โ€ข Diastolic BP: 80 mmHg (70โ€“93)
โ€ข Heart rate: 96 bpm (82โ€“108)
โ€ข NYHA Class at Admission:
โˆš Class I: 4.2%
โˆš Class II: 8.5%
โˆš Class III: 29.6%
โˆš Class IV: 57.7%
โ€ข De novo HF: 64.2%

Lab investigations โ€” Median (IQR), pg/mL

โ€ข NT-proBNP: 1,879 (140โ€“6,305)
โ€ข NT-proBNP (measured or BNP-converted): 1,993 (140โ€“7,164)

ECG: Atrial fibrillation/flutter - 20.9%

Echocardiography โ€” Median (IQR)

โ€ข LVEDD: 58 mm (49โ€“65)
โ€ข LVEF: 38% (28โ€“55)

Rx at Discharge:

Among pts with available data

โ€ข ฮฒ-blockers: 76.9%
โ€ข RAAS inhibitors: 73.9%
โ€ข MRAs: 71.9%
โ€ข SGLT2 inhibitors: 54.7%

Fewer than 50% of pts reached target doses across all major HF medication classes.

Key Outcomes:

โ€ข In-hospital mortality: 8.7%
โ€ข 30-day mortality: 11.1%
โ€ข 180-day mortality: 20.6%
โ€ข Lost to follow-up before 180 days: 33.7%

Key Takeaways:

1. Hypertensive heart disease is now the leading cause of acute HF in Africa.

2. Pts are relatively young but face high short- and long-term mortality.

3. Use of GDMT is high, but target doses are achieved in fewer than half of pts.

4. Large loss to follow-up underscores the need for strong post-discharge follow-up systems.

5. Greater focus is needed on prevention, access to cardiac care, GDMT optimization, & continuity of care.

https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(26)01657-0/abstract?rss=yes

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