07/08/2026
Deleterious Effects of Gadolinium in the Bone Marrow:
- Marrow hypoplasia and anaemia
- Leukopenia
- Hypophophataemia
- Marrow shortening
- Bone marrow infarction
- Increased Gd T1 hyperintensity on subsequent Mris
Gd and the Bone Marrow:
1. Gadolinium depositis in the bone marrow and has a predilection for doing so
2. Gadolinium is toxic to the bone marrow and marrow producing blood cells,
3. Gadolinium adversely affects calcium phosphate homeostasis in bone
4. Gadolinium structurally impaired Bone Marrow integrity
Objective Monthly scanning with triple-dose gadopentetate dimeglumine has been shown to be associated with progressive increases in bone T1 hyperintensity, hypo...