Andrea Giachetti, FNP-C - Functional Reset NP

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Andrea Giachetti, FNP-C - Functional Reset NP Functional Medicine NP | Oregon 🌿
Real answers for gut, hormone & metabolic issues your labs say are "normal" but your body says otherwise.

Telehealth statewide | In-home visits, Rogue Valley
đź’¬ DM "CLARITY" to get started
👉 Book: www.functionalresetnp

10/22/2026

If your PMS keeps getting worse and every answer you get is some version of “just take ibuprofen,” stay with me for a minute. Your gut may be playing a bigger role than anyone has told you.

Your liver has a packaging system called glucuronidation. It takes things your body is done with, like used estrogen, testosterone, many medications, environmental chemicals, and some mold toxins, and wraps them up so they can be removed. Some of those packages leave through your urine. Others are sent into your gut to leave with your stool.

That’s where your gut bacteria come in. Certain strains make an enzyme called beta-glucuronidase, and it rips those packages back open, like raccoons tearing into the trash bags you just set out on the curb. Once the bag is open, what was inside can be reabsorbed into your bloodstream instead of leaving your body.

High beta-glucuronidase has been linked to:

→ Estrogen recycling, which can add to symptoms like heavy periods, breast tenderness, and a rough premenstrual week

→ Constipation, since slower transit gives the enzyme more time to work

→ Stronger gut side effects from certain medications that get reactivated in the intestine

→ Some toxins hanging around longer before they clear

Researchers are also studying its role in hormone-sensitive cancers like breast cancer, and in colon cancer. The research is still early, and a link isn’t the same as a cause. It’s a number I’d rather know than guess at.

And you don’t have to guess. A comprehensive stool test measures your beta-glucuronidase activity and shows which bacteria are living in your gut, including types known to produce it. I run this testing in my practice because it gives us real data on whether your gut is part of your hormone picture.

From there, we build a targeted gut protocol around your results. Yours, not a generic supplement list you found online.

If you’re ready for answers, DM me “GUT” and I’ll send you the details on stool testing and working with me.

📍Telehealth across Oregon | In-home consults within the Rogue Valley



“Your LDL is high. I’ve already sent the statin over to your pharmacy. Any questions?”If you’ve heard some version of th...
10/20/2026

“Your LDL is high. I’ve already sent the statin over to your pharmacy. Any questions?”

If you’ve heard some version of that, you know how it goes. The visit is wrapping up, you nod along, and the real questions don’t show up until you’re sitting in your car in the parking lot.

So let me say this plainly. Wanting to understand a medication you might take for decades isn’t being difficult. It’s being a good patient.

A cholesterol rise in perimenopause and menopause is common enough that it should almost be expected. That’s exactly why it deserves a closer look instead of a reflex. Even the newest cardiology guidelines, updated in 2026, focus on calculating your actual risk and making the decision with you, not reacting to one LDL value.

None of this makes statins the bad guy. For some women they’re absolutely the right call, and the new guidelines support starting them earlier when risk is truly high. You just deserve to know where you stand before you decide.

Swipe through for the questions I’d want answered before that prescription gets filled. Then save it so they’re ready for your next appointment.

I’m curious: were you offered a statin before anyone checked your ApoB, Lp(a), or thyroid? Tell me below 👇

Already taking one? Please don’t stop it on your own. Bring these questions to your prescriber instead.

Follow along for more on hormones, metabolism, and the labs midlife women deserve to have run.

Want a deeper look at your own numbers? Comment “LABS”.

📍Telehealth across Oregon | In-home consults within the Rogue Valley

Have you ever driven home from an appointment replaying the whole conversation in your head? Wondering if you downplayed...
10/18/2026

Have you ever driven home from an appointment replaying the whole conversation in your head? Wondering if you downplayed it. Wishing you'd brought notes. Thinking maybe you just explained it wrong.

You didn't explain it wrong.

And your provider probably didn't do anything wrong either. Conventional medicine is excellent at catching disease and handling emergencies, and I'm grateful it's there when we need it. It just wasn't built to figure out why a woman with "normal" labs is fighting to keep her eyes open at her desk by 2 p.m.

That's the gap I work in.

I just put up a new blog post that goes a lot deeper on this. It covers why normal and optimal aren't the same thing, which labs usually get skipped, and what I look for when everything comes back "fine." You'll find it on my website. Read it here: https://www.functionalresetnp.com/blog/normal-labs-but-still-feel-terrible

Now tell me in the comments: which of these have you heard? I have a feeling a lot of you are about to type "all of them."

And if you're ready for someone to actually dig in, comment LABS and I'll DM you how to get started.

📍 Telehealth across Oregon | In-home visits in the Rogue Valley

10/17/2026

Nothing about your diet changed. So why did your cholesterol?

If your numbers started climbing in your late 40s, the full answer probably isn’t on the standard lipid panel your doctor ran. Falling estrogen changes how your liver clears cholesterol, and these same years often shift your thyroid, your insulin, and the type of LDL you’re making. Even your HDL can look great on paper and still not be pulling its weight.

This matters more than most women realize. Heart disease killed over 314,000 US women in 2020, about 1 in 5 female deaths. Breast cancer is expected to take around 42,000 this year. That’s roughly seven times as many, yet most of us grew up with far more breast cancer awareness.

Women have been underrepresented in the big statin trials (and medicine in general) for decades. Statins do lower the risk of heart events, but for women without existing heart disease, the evidence that they help us live longer is much thinner than we’ve been told. One paper concluded the clearest survival benefit showed up mainly in middle-aged men.
Check it out here 👉 PMID: 32861373

Before you decide if a statin is right for you, here’s where I’d start:

📌 Advanced lipid panel + ApoB
📌 Check Lp(a) at least once. It’s largely genetic and rarely tested
📌 Full thyroid panel, not just TSH
📌 hsCRP and homocysteine
📌 Fasting insulin alongside your A1C
📌 Eat protein at every meal and aim for 30g of fiber a day
📌 Lift heavy a few times a week
📌 Dealing with menopause symptoms? Bring up hormone therapy, even if it’s been brushed off before

Statins absolutely have their place, especially with very high LDL, diabetes, plaque, or existing heart disease. They just work best as a decision based on the full picture and your own risk, not a single number.

I post weekly about hormones, metabolism, and the labs women deserve in midlife. Follow along so the next one finds you.

Ready for someone to actually dig into your numbers? DM me the word LABS and let’s look at the whole picture together.

📍Telehealth throughout Oregon | In-home consults in the Rogue Valley

Perimenopause is the only game show where you lose sleep, lose your words, and still go home with a printout that says y...
10/16/2026

Perimenopause is the only game show where you lose sleep, lose your words, and still go home with a printout that says you’re fine.

You came in with night sweats, a brain that keeps dropping words mid-sentence, and a waistband that quit cooperating sometime last spring. What you left with was “everything looks normal” and a suggestion to manage your stress. (Thanks. Hadn’t thought of that.)

Then the worst part kicks in on the drive home. You start wondering if you made the whole thing up.

I promise you, you didn’t.

Most lab reference ranges are built from the middle 95% of people who got tested. Nobody checked how those people actually felt. So “normal” can simply mean you’re about as worn out as everyone else in the sample. Not very helpful.

Perimenopause makes it even messier. Estrogen can swing hard from one week to the next, which turns a single blood draw into a snapshot of a moving target. One decent-looking number from one random morning tells me very little about the other 29 days.

That’s why I dig further. A full thyroid panel instead of TSH alone, the one basic screening test most clinicians stop at. Ferritin, which shows how much iron your body has in storage. Fasting insulin, one of the earliest signs that blood sugar is starting to drift. hs-CRP, which picks up low-grade inflammation in the body. Then I read every result against optimal ranges, not the “you’re not sick yet” range.

What you get out of all that isn’t a prettier lab report. It’s sleeping through the night. Finishing your own sentences. Getting to 3pm without a third coffee. A scale that finally moves when you put in the work.

If your labs keep saying “fine” and your body keeps filing complaints, comment LABS and I’ll send you the details.

📍 Telehealth across Oregon | In-home consults in the Rogue Valley

Save this for your next appointment, and send it to the friend who keeps hearing “it’s just your age.”

You’ve seen the specialists and done the scans, and not one of them asked what was happening in your life when all of th...
10/16/2026

You’ve seen the specialists and done the scans, and not one of them asked what was happening in your life when all of this started.

That question is a big part of why I practice functional medicine.

Specialization has real value. If something is wrong with your heart, you want someone who knows hearts inside and out. But the further medicine zooms in, the easier it is to lose the person in the frame. You become a thyroid. A gut. A row of flagged labs that gets passed along to the next office.

Functional medicine taught me to keep asking why. Why is this happening? What changed right before it started? And what’s sitting upstream of the symptom that nobody has looked at yet? Those questions usually lead somewhere a lab panel can’t.

After twenty years in clinical medicine, I don’t believe illness is random. It isn’t only bad genes or unlucky biology. Gabor Maté describes it as an expression of a whole life lived, and I watch that play out with patients every week. The relationship that slowly wore you down. Years of running on stress hormones. Everything your body absorbed that you never had room to process.

This matters most with autoimmune conditions (when the immune system starts attacking your own tissue) and chronic symptoms that don’t fit neatly into any diagnosis. If no provider has ever asked about your stress history, your early life, or what was going on when your symptoms first showed up, that’s not a small oversight. A major piece of your clinical picture is missing.

Your body has kept a record of everything you’ve been through. Good care means reading all of it, not just the page that printed with your lab results.

That’s how I practice. If you’ve been bounced from specialist to specialist and still feel unseen, send me a DM. Let’s look at the whole picture together.

📍 Telehealth across Oregon | In-home consults in the Rogue Valley

10/15/2026

Eleven months of chronic diarrhea. A normal colonoscopy, normal stool cultures, and still six loose stools every day.

Those tests did their job. They ruled out some serious things, and that matters. They just weren’t designed to show what was happening with her gut bacteria and digestion.

We ran a GI-MAP, and the results filled in those gaps. They showed bacterial overgrowth, missing beneficial flora, gut inflammation, and digestion that needed real support. We built her protocol around those exact findings, and five weeks later she’s gone from six loose stools a day to three formed ones.

Her words: “I feel 10% away from perfect.” She’s delighted. So am I.

I love wins like this. If you’re still dealing with gut symptoms after your workup came back normal, DM me GUT. There’s often more to look at.

📍 Telehealth across Oregon | In-home consults in the Rogue Valley

10/14/2026

You eat well. You work out. You’ve added the protein, cut back on the w**e, tried the fasting window. And perimenopause still found a way to move the scale, steal your afternoons, and send cravings at 3 p.m. like it’s a scheduled appointment.

Then your labs come back and someone tells you everything looks fine.

I hear a version of this every week from women who run companies, raise families, and handle more before noon than most people do all day. They aren’t confused about what to eat. They’re tired of being the only one who believes something is off.

Here’s what “fine” usually means: the standard panel was run, nothing got flagged, and nobody asked a single follow-up question.

My practice works differently. We start with the labs most women have never been offered. Fasting insulin, which can catch insulin resistance years before your A1c shows a problem. A full thyroid panel, not just TSH. Cortisol patterns across your day. S*x hormones. Comprehensive gut testing when your symptoms point there. Then we look at the whole picture, including how you sleep, eat, train, and carry stress.

And you won’t get a PDF and a “good luck.” You get real time with me, a plan built around the life you actually have, and ongoing support as we adjust along the way. And definitely not a meal plan you’ll abandon by Thursday.

None of this is in your head. It’s in your labs, and nobody has looked closely enough yet. You’ve built a life that runs on your energy. How you feel in your body shouldn’t be an afterthought.

Comment METABOLISM and I’ll send you the labs I’d want to see first, or DM me to talk about working together.

📍 Telehealth across Oregon | In-home consults in the Rogue Valley

Address

105 Bolz Road
Phoenix, OR
97535

Opening Hours

Monday 8am - 4pm
Tuesday 8am - 4pm
Wednesday 8am - 4pm
Thursday 8am - 4pm

Telephone

+14584886024

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