Aperiomics

Aperiomics Aperiomics' mission is to change EVERYTHING about how infections are tested. The only company identifying every known pathogen in ONE test! Aperiomics is the only company identifying every bacteria, DNA virus, fungi and parasite in one test.
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Clinicians and patients call on Aperiomics to identify infectious diseases that other tests cannot identify. The only company of its kind and scope in the world, Aperiomics identifies every known pathogen (bacteria, virus, fungi or parasite) in a single test through next-generation sequencing of the DNA or RNA in any sample (patient, environmental, etc.). The complete genetic fingerprint of that sample is then compared to the Aperiomics Microbial Database™- the most comprehensive database of microorganisms, including the world’s largest collection of pathogens. This breakthrough is only possible through Aperiomics and can be used to identify unknown/chronic infections, limit the use of antibiotics and solve difficult medical cases. Patients and their families often contact Aperiomics directly after hearing about our successes in helping others. Aperiomics was named Life Sciences Innovators of the Year in 2016 and a finalist in the 2017 Greater Washington Innovation Awards. For more information, visit www.aperiomics.com or call (703) 229-0406.

Mission: To change EVERYTHING about how infections are identified!

Operating as usual

When I was recently presenting as a finalist at the NASA iTech Competition, it was exciting to think how Aperiomics Meta...
11/03/2020
How many alien civilizations are out there? A new galactic survey holds a clue.

When I was recently presenting as a finalist at the NASA iTech Competition, it was exciting to think how Aperiomics Metagenomic testing could potentially help identify DNA on new worlds, such as the ones in this article. #Aperiomics #NASAiTech

The Milky Way is full of habitable real estate, with roughly half of all sunlike stars hosting Earth-size worlds that could be friendly to life.

Excited to share that Aperiomics has been nominated for two different Technical.ly DC Awards! year's program aims to hig...
10/26/2020
DC, meet your nominees for the 2020 Technical.ly Awards - Technical.ly DC

Excited to share that Aperiomics has been nominated for two different Technical.ly DC Awards! year's program aims to highlight the people, companies and ideas making their communities better amid unfathomable challenges. For “Innovation of the Year,” Aperiomics’ Xplore-COVID-19 testing kit was nominated. Aperiomics CTO and Co-Founder Alvin Chen was also nominated for “Technical Leader of the Year.”

Much like last year, the awards will be decided by popular vote! We encourage you to participate. Voting is opens today and winners will be announced on Friday, October 30th via Twitter

For each of our six categories — Invention, Impact Leader, Technical Leader, Culture Builder, Startup and Growth Company of the Year — tell us who is making the biggest impact in your local tech and entrepreneurship community. Voting is open through Oct. 26.

We will be presenting our Abstract at the 2020 ID Week!  Come join us at our virtual booth and see our Poster#1681 on Fe...
10/21/2020

We will be presenting our Abstract at the 2020 ID Week! Come join us at our virtual booth and see our Poster#1681 on Female Urinary Metagenomic Analysis and Natural Language Processing Enhances the Infectious Diagnostic Yield in Precision Medicine #idweek2020, #Aperiomics, #DrCrystalIcenhour

I'm honored to be speaking at the 6th Annual BioHealth Capital Region Forum.  Come join us, it's Free and virtual. #BHCR...
10/15/2020

I'm honored to be speaking at the 6th Annual BioHealth Capital Region Forum. Come join us, it's Free and virtual. #BHCRforum2020, #aperiomics, #DrCrystalisenhour

Aperiomics continues our series A funding round with a welcome boost from The Launch Place, a venture development organi...
10/06/2020
Launch Place makes its 20th investment

Aperiomics continues our series A funding round with a welcome boost from The Launch Place, a venture development organization based in Research Triangle Park, NC. We're proud to call them partners as we strive to disrupt infectious disease diagnostics:

http://www.chathamstartribune.com/news/article_2e9e8fa2-0726-11eb-8cb8-7b7a26c1bb19.html

The Launch Place, a venture development organization with offices in Danville and Research Triangle Park, N.C., has invested $150,000 from their Seed Fund II in Virginia-based healthcare startup Aperiomics. This

10/06/2020
2020 NASA iTech Cycle I Forum - Aperiomics

We had a great time at NASA's iTech competition last week! Check out our finalist presentation below to learn more about how we're pioneering infectious disease and microbiome testing:
👩‍🔬 🦠 🚀
https://youtu.be/uuNtosk8kBo

Aperiomics Inc. Xplore-PATHO Microbial Identification Technology Focus Area: X-Factor Innovations A technology that could identify every known microorganism,...

A new study published in Nature has found that treating pregnant mice with antibiotics disrupts the development of the f...
09/25/2020
How microbes in a mother's intestines affect fetal neurodevelopment

A new study published in Nature has found that treating pregnant mice with antibiotics disrupts the development of the fetal brain due to decreased gut microbiome metabolites. Supplementing several of these metabolites directly restored axon development:

https://www.sciencedaily.com/releases/2020/09/200923164601.htm

During pregnancy in mice, the billions of bacteria and other microbes that live in a mother's intestines regulate key metabolites, small molecules that are important for healthy fetal brain development, biologists report. Scientists had not known until now whether the maternal gut microbiota influen...

In a new study with mice, researchers have found that obstructive sleep apnea (OSA) reshapes the gut microbiome in a way...
09/24/2020
Gut microbiome plays important role in sleep regulation: Transplanted bacteria from sleep-apnea mice caused sleep changes in recipient mice

In a new study with mice, researchers have found that obstructive sleep apnea (OSA) reshapes the gut microbiome in a way that is transferable. Furthermore, mice receiving the OSA microbiota slept longer and more often, suggesting increased sleepiness:
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https://www.sciencedaily.com/releases/2020/09/200923124804.htm

Obstructive sleep apnea (OSA) affects more than one billion people worldwide. Evidence suggests OSA can alter the gut microbiome (GM) and may promote OSA-associated co-morbidities, including diabetes, hypertension and cognitive problems. Researchers have discovered how OSA-related sleep disturbances...

Using ~1,000 samples from the American Gut Project, researchers have found specific bacteria to be highly predictive of ...
09/22/2020
Gut microbiome data may be helpful in routine screening of cardiovascular disease

Using ~1,000 samples from the American Gut Project, researchers have found specific bacteria to be highly predictive of cardiovascular disease (CVD), opening the possibility of using a patient's gut microbiome data for yet another important health index:

https://www.sciencedaily.com/releases/2020/09/200910150336.htm

Previous studies have found the human gut microbiome, bacteria in the gastrointestinal tract, is associated with cardiovascular disease (CVD). This study used machine learning to analyze data from nearly 1,000 stool samples from people with and without CVD. Results show potential for developing a co...

09/18/2020
Clinical Laboratory Technologist III - Sterling, VA 20166 - Indeed.com

Aperiomics is currently looking for a Clinical Laboratory Technologist III to join our growing team! Please follow the link below to view the position details. All qualified candidates are encouraged to apply:

https://www.indeed.com/job/clinical-laboratory-technologist-iii-50306df6eaa3dab9

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In a recent attempt to link the gut microbe to overall health, Mayo Clinic researchers have developed a Gut Microbiome H...
09/18/2020
Scientists develop mathematical index to distinguish healthy microbiome from diseased

In a recent attempt to link the gut microbe to overall health, Mayo Clinic researchers have developed a Gut Microbiome Health Index using nearly 4,300 microbiome samples. This led to a healthy microbiome signature composed of 50 microbial species:
🦠👩‍🔬🧫
https://www.sciencedaily.com/releases/2020/09/200915140127.htm

What causes some people to develop chronic diseases such as rheumatoid arthritis, cancer and metabolic syndrome while others stay healthy? A major clue could be found in their gut microbiome -- the trillions of microbes living inside the digestive system that regulate various bodily functions.

More than half of women will have a UTI at some point in their lives. Successful treatment hinges on correctly identifyi...
09/16/2020
Clean Catch Urine: Crucial for an Accurate UTI Test

More than half of women will have a UTI at some point in their lives. Successful treatment hinges on correctly identifying the causative pathogen and for many tests, such our Xplore-PATHO® Urine test, that means a properly collected clean catch sample:

https://liveutifree.us16.list-manage.com/track/click?u=8a5949c3356bba5c9e8fd7798&id=e8715e82a4&e=76f6b2046a

A clean catch urine sample can mean the difference between an accurate UTI test, and 'contamination'. Learn how to collect one.

Researchers have found that warmer climates have a positive impact on bone density with implications for osteoporosis. S...
09/15/2020
Stronger bones thanks to heat and microbiota

Researchers have found that warmer climates have a positive impact on bone density with implications for osteoporosis. Surprisingly, the benefit was found to be due to the effects of heat on the gut microbiome and was transferable via the microbiome:
🦠🦴
https://www.sciencedaily.com/releases/2020/09/200911093027.htm

Osteoporosis is characterized by a deterioration of the bones and an increased risk of fractures. With one third of postmenopausal women affected, it is a major public health problem. A research team has observed that exposure to warmer ambient temperatures increases bone strength and prevents the l...

It's official, Aperiomics is a 2020 NASA iTech Finalist  🥳 Join us as we present with the other finalists during the two...
09/11/2020

It's official, Aperiomics is a 2020 NASA iTech Finalist 🥳
Join us as we present with the other finalists during the two-day online forum from October 1-2. NASA iTech will announce three winners as the forum wraps up on the 2nd. Hope to see you there:

https://livestream.com/nasaitech

A new study looking at the gut microbiome in Huntington's disease has found strong correlations between the two. In part...
09/09/2020
Gut Microbiome Seen to Differ in People With Huntington’s or at...

A new study looking at the gut microbiome in Huntington's disease has found strong correlations between the two. In particular, symptomatic patients with low numbers of a species called Eubacterium hallii tended to show more severe motor symptoms:
🧫 🔬 👨‍🔬
https://huntingtonsdiseasenews.com/2020/08/25/gut-microbiome-differs-people-with-huntingtons-or-at-disease-risk-study-says/

Microbes in the gut of people with Huntington's or likely to develop this disease appear to differ from healthy peers, opening the door to potential new biomarkers and therapeutic targets, according to a recent study. The study, "Gut dysbiosis in Huntington’s disease: associations between gut...

Join us and leaders in industry and academia as we discuss building a resilient community!Hear from leaders addressing i...
09/04/2020

Join us and leaders in industry and academia as we discuss building a resilient community!

Hear from leaders addressing inclusion and diversity and the impacts for our industry at our virtual half-day conference. Get inspired about the future of our industry and the path being carved by young female leaders through mentorship. Share in opportunities for networking, discussions on leadership and life challenges, experiences in the current environment, how to “pivot” to capture those opportunities. Discover new healthcare and research policies that have changed in these unique times. Join us at the Women Building Bio Conference this September #womenbuildingbio

Researchers looking at the links between dysfunctional sleep, blood pressure, and the gut microbiome have found that con...
09/03/2020
UIC research discovers links among poor sleep, high blood pressure, gut microbiome

Researchers looking at the links between dysfunctional sleep, blood pressure, and the gut microbiome have found that consistent sleep disruptions in rats led to increases in blood pressure and more inflammatory gut microbes that were not easily reversed:

https://www.eurekalert.org/pub_releases/2020-09/uoia-urd090220.php

University of Illinois Chicago researchers have found associations among disrupted sleep, elevated blood pressure and changes in the gut microbiome.The research aimed to determine whether a 28-day period of disrupted sleep changed the microbiota in rats. The researchers also sought to identify biolo...

Using one of the fastest supercomputers in the world, researchers analyzing the genetics of COVID-19 have uncovered a ne...
09/03/2020
A Supercomputer Analyzed Covid-19 — and an Interesting New Theory Has Emerged

Using one of the fastest supercomputers in the world, researchers analyzing the genetics of COVID-19 have uncovered a new hypothesis, bradykinin storms, for how the virus is able to cause such devastating and diverse symptoms:
🔬 👩‍🔬 🦠
https://elemental.medium.com/a-supercomputer-analyzed-covid-19-and-an-interesting-new-theory-has-emerged-31cb8eba9d63

A closer look at the Bradykinin hypothesis

09/02/2020
Microbiota-derived metabolite promotes HDAC3 activity in the gut

Showcasing an aspect of the symbiotic nature of some gut microbiota, researchers have revealed that inositol trisphosphate, a metabolite of some commensal bacteria including E. coli, promotes epithelial barrier repair:
🦠 🔬 🧫
https://www.nature.com/articles/s41586-020-2604-2

The coevolution of mammalian hosts and their beneficial commensal microbes has led to development of a symbiotic host-microbiota relationship1. Epigenetic machinery permits mammalian cells to integrate environmental signals2, however, how these pathways are finely tuned by diverse cues from commensa...

In one of the largest projects to date on the gut virome, researchers have found that the diversity of gut bacterial vir...
08/26/2020
Gut Viromes Are Highly Individualized, Yet Reveal Shared Patterns

In one of the largest projects to date on the gut virome, researchers have found that the diversity of gut bacterial viruses, aka phages, peaks in adulthood and decreases as we age. This diversity was also correlated with overall health:
🦠🔬👩‍🔬
https://www.genengnews.com/news/gut-viromes-are-highly-individualized-yet-reveal-shared-patterns/

Gut Virome Database powers metagenomic analyses and reveals age-dependent patterns of virome diversity in the human gut

A new study looking at the structure of the gut microbiome reveals how microbial communities can remain resilient despit...
08/25/2020
Stronger together in the microbiome: How gut microbes feed each other to overcome dietary deficiencies, change host behavior, and improve reproduction

A new study looking at the structure of the gut microbiome reveals how microbial communities can remain resilient despite dietary deficiencies and influence the food preferences of their hosts:
🦠 🧫 🔬
https://www.eurekalert.org/pub_releases/2020-08/ccft-sti082420.php

To study how the microbiome affects their host behavior, a group of researchers at the Champalimaud Centre for the Unknown, in Lisbon - Portugal, used the fruit fly combined with high-tech tools to show that two gut bacteria establish a metabolic cross-feeding that enables them to grow in diets that...

While investigating new methods of vaccine delivery, researchers have found that fungal β-glucan particles loaded with S...
08/21/2020
Vaccine that harnesses antifungal immunity protects mice from staph infection

While investigating new methods of vaccine delivery, researchers have found that fungal β-glucan particles loaded with Staphylococcus aureus proteins were able to induce antibodies and confer protection from S. aureus infection in mice:
🦠 🐁 🔬
https://www.sciencedaily.com/releases/2020/08/200820143237.htm

Immunization of mice with a new vaccine consisting of fungal particles loaded with Staphylococcus aureus (S. aureus) proteins protects mice against S. aureus infection, according to a new study.

A new study looks at the links between asthma and bronchial fungal species, aka the mycobiota. Researchers concluded tha...
08/20/2020
The airway fungal microbiome in asthma

A new study looks at the links between asthma and bronchial fungal species, aka the mycobiota. Researchers concluded that fungal species complexes such as Aspergillus niger and Cryptococus humicola may play unexpected roles in the pathogenesis of asthma:

https://onlinelibrary.wiley.com/doi/abs/10.1111/cea.13722?af=R

Background Fungal involvement in asthma is associated with severe disease. The full spectrum of fungal species in asthma is not well described and is derived largely from insensitive culture techniq...

In a new study on kidney cancer and the gut microbiome, researchers have found that patients who benefited the most from...
08/19/2020
Greater Diversity in Gut Microbiome Associated with Better Cancer Immunotherapy Outcomes

In a new study on kidney cancer and the gut microbiome, researchers have found that patients who benefited the most from cancer treatment had more gut microbiome diversity or a higher abundance of a bacterium called Akkermansia muciniphila:
🦠 🔬 🧫
https://www.clinicalomics.com/topics/oncology/immunotherapies/greater-diversity-in-gut-microbiome-associated-with-better-cancer-immunotherapy-outcomes/

The findings showed that the greater the variety of organisms found in a patient's gut microbiome, the greater the benefit of the therapy to that patient. It also suggested that modulating the gut microbiome during treatment could affect a patient’s responses to therapy.

New research has found that the presence of certain bacteria in the microbiome, those producing a metabolite called inos...
08/17/2020
Researchers discover the microbiome's role in attacking cancerous tumors

New research has found that the presence of certain bacteria in the microbiome, those producing a metabolite called inosine, were able to significantly increase the effectiveness of chemotherapy for several types of cancer :

https://www.sciencedaily.com/releases/2020/08/200813144920.htm

Researchers have discovered which gut bacteria help our immune system battle cancerous tumors and how they do it. The discovery may provide a new understanding of why immunotherapy, a treatment for cancer that helps amplify immune response, works in some cases, but not others. The findings show comb...

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45925 Horseshoe Dr
Sterling, VA
20166

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Monday 09:00 - 17:00
Tuesday 09:00 - 17:00
Wednesday 09:00 - 17:00
Thursday 09:00 - 17:00
Friday 09:00 - 17:00

Telephone

(703) 229-0406

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Aperiomics is a precision pathogen testing company that is changing EVERYTHING about how infections are identified. Aperiomics’ Xplore-PATHO™ is a combination of deep metagenomic sequencing and proprietary bioinformatic analysis that can identify 37,000+ microorganisms in a single test. This cutting-edge technology is delivered as a service and detects every known bacteria, virus, parasite, and fungus.

Xplore-PATHO™ is a service that tests samples (human, animal, plant) for the presence of every known microorganism (bacteria, DNA virus, parasite, and fungi) in a single test. This platform technology has broad application across diverse markets such as clinical, agriculture, environment, industry, and veterinary. The impact of Aperiomics’ technologies is substantial due to this unique approach to microbe detection. Instead of blindly probing for a proverbial ‘needle in a haystack’, Aperiomics’ approach analyzes the entire ‘haystack’, harnessing the power of deep metagenomic sequencing and bioinformatics to identify every ‘needle’. Xplore-PATHO™ is transformative and is changing pathogen identification forever.

Existing pathogen testing, simply put, is inadequate; up to 80% of infections go undiagnosed. Undiagnosed infection costs the US economy billions each year (undiagnosed fungi alone cost $26B). Further, existing tests require one to know what they are looking for; Aperiomics’ approach identifies every known microorganism, even if you don’t know what you are looking to find. Deep sequencing is the future of pathogen testing and has already disrupted cancer testing markets. Data analysis for sequencing is often more expensive than the generation of raw sequencing data and is a major bottleneck to adoption in pathogen testing. For sequencing to reach its full potential of revolutionizing pathogen identification, data analysis must be robust, simplified, and automated. Aperiomics’ Xplore-PATHO™ does just this, providing a cost-effective method to detect 37,000+ microorganisms in ONE test.

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Comments

Congrats on being featured in our 2020 Best Tech Startups in Sterling! http://thetechtribune.com/best-tech-startups-in-sterling/
I want to do the Aepriomics test but I dont know if it will help. The medical system has no diagnosis for me and my symptoms seems degenerative. My doctor wanted to do Aperiomics but as someone who has alread doe the conninham panel and gut biome testing I want to know why this will be more helpful.
Do you guys pick up on diseases also...or illnesses like meningitis?
Does medicare cover test?
I have questions as a provider (I’m an NP). I could not access the clinician profile, who can answer my questions??
Please update your website to reflect the accurate timeline for results. We’ve been waiting 19 days for results and the website claims they will be back in 10-14 days. Anticipation is very difficult but when there is an accurate timeline it does help offset some of the anxiety and stress of waiting.
I am considering having a few samples sent in for testing. My doctor and I will need some support, meaning (medical guidance) on the test results. Can you provide this?
Hi, I got your urine test today and have been off abx since 3 days but are still on probiotics. I really would like to take the test as soon as possible and then go on abx again, but can they interfere much with the results? I read on your site it mostly was for stool samples but not sure for UTIs. Have had an embedded UTI since 4 months. Thank you 🦋
Has anyone with microscopic colitis ever tried this test? It's considered an auto immune disease, not like other colitis.
Looking forward to getting tested
I am happy to see this for Medical Doctors, the natural world of medicine has used similar technologies for years. At least now they can use the correct antibiotic and not harm us guessing.
Check out their website