10/03/2026
Can just ONE set per exercise build impressive muscle in trained lifters? 🤔
A recent study had resistance-trained men and women perform:
🏋️ One set per exercise
📅 Twice per week
⏱️ For 8 weeks
The result? 📊
Both groups gained muscle, regardless of whether they trained to failure or stopped two reps short.
But here’s what I found most interesting...
The amount of muscle growth reported.
The failure group increased mid-quadriceps muscle thickness by about 0.37 cm while performing just six weekly sets for the quadriceps. That’s substantially more growth than many studies have reported despite using much higher training volumes. That doesn’t automatically make these findings incorrect.
It simply means we should place them in the context of the broader literature before dramatically changing our recommendations.
Some important questions remain:
👉🏼Why do some labs consistently report much larger hypertrophy responses than others?
👉🏼Are methodological differences influencing the results?
👉🏼Should these findings be replicated before we conclude that very low volumes produce this magnitude of muscle growth?
In the full YouTube video 🎥 I discuss:
• The study design
• Why the hypertrophy results caught my attention
• How these findings compare with previous research
• Why context matters when interpreting a single paper
• Practical takeaways for your own training 💪🏽
Now… A question for you!
🧐Do you think four to six weekly sets are enough to maximize muscle growth in trained lifters, or would you like to see these findings replicated first? Let me know in the comments below! 💬