Center for Surgical Science

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Center for Surgical Science The Center for Surgical Science aims to improve the treatment of surgical patients resulting in minimal morbidity and optimal clinical outcomes.

Operating as usual

We are looking for a medical student to do research on surgery and oncological biomarkers.Check out the job posting and ...
30/05/2021
Medicinstuderende søges til forskning indenfor kirurgi og onkologiske biomarkører | Center for Surgical Science (CSS)

We are looking for a medical student to do research on surgery and oncological biomarkers.
Check out the job posting and apply before June 15, 2021:
https://centerforsurgicalscience.dk/projects-archive/medicinstuderende-soges/

Center for Surgical Science (CSS) på Sjællands Universitetshospital (SUH) i Køge søger en medicinstuderende på kandidatdelen med interesse for kirurgi og onkologiske biomarkører til et forskningsår/forskningssemester.

A big milestone in our journey towards #personalizedmedicine in Denmark!In this #cohort study, a multivariable patient-l...
25/05/2021
Prediction of 90-day mortality after surgery for colorectal cancer using standardized nationwide quality-assurance data

A big milestone in our journey towards #personalizedmedicine in Denmark!
In this #cohort study, a multivariable patient-level model was developed following the #OHDSI framework on data from the Danish #colorectalcancer register, with impressive results on the prediction of 90-day mortality after colorectal surgery.
https://academic.oup.com/bjsopen/article/5/3/zrab023/6272169

Early prediction of postoperative mortality is essential for tailoring postoperative treatment and care. In this nationwide study including 32 927 patients unde

On the occasion of the #WorldImmunizationWeek we reflect on the vast potential of immunizing not only regarding viral di...
25/04/2021
Immunizing not only for viral disease prevention but also cancer recurrence prevention | Center for Surgical Science (CSS)

On the occasion of the #WorldImmunizationWeek we reflect on the vast potential of immunizing not only regarding viral disease prevention, but also cancer recurrence prevention.
#vaccinesbringuscloser

Take a look here:

https://centerforsurgicalscience.dk/articles/immunizing-not-only-for-viral-disease-prevention-but-also-cancer-recurrence/

No doubt that this year’s World Immunization Week follows up on a milestone in the history of mankind where a collective effort to prevent a global pandemic from escalating has been seen.

Listen to this interesting podcast from Altinget.dk where Ismail Gogenur, Senior Consultant and Director of Center for S...
18/03/2021
How can Big Data and Artificial Intelligence affect clinical research in the future? | Center for Surgical Science (CSS)

Listen to this interesting podcast from Altinget.dk where Ismail Gogenur, Senior Consultant and Director of Center for Surgical Science at Sjællands Universitetshospital, Køge and Nikolai Brun, Senior Consultant, Chairman of the Task Force for Big Data, EMA, Head of Unit for Medical Evaluation & Biostatistics at Lægemiddelstyrelsen (Danish Medicines Agency) discuss with Chris Lehmann about how #bigdata and #AI could affect the clinical research of the future.
https://centerforsurgicalscience.dk/news/altinget-podcast/

Listen to the podcast from Altinget where Ismail Gögenur, Senior Consultant and Director of Center for Surgical Science and Nikolai Brun, Senior Consultant, Chairman, Task Force for Big Data, EMA, Head of Unit, Medical Evaluation & Biostatistics (Danish Medicines Agency) explain how Big Data and AI...

Are you a postdoctoral scientist interested in #translationalresearch? Would you like to work in a newly established res...
04/03/2021
Postdoctoral scientist | Center for Surgical Science (CSS)

Are you a postdoctoral scientist interested in #translationalresearch? Would you like to work in a newly established research laboratory, become a part of a multidisciplinary group of more than 40 researchers and lead the team for translational research?
Then we have the perfect opportunity for you!
Read more and send in your application before March 15, 2021:
https://centerforsurgicalscience.dk/projects-archive/postdoctoral-scientist/

We are looking for a postdoctoral scientist to be part of Center for Surgical Science (CSS) and to lead a new research laboratory.

Another exciting #jobopportunity at the Center for Surgical Science! We are looking for an experienced and dedicated #pr...
06/01/2021
Project Consultant | Center for Surgical Science (CSS)

Another exciting #jobopportunity at the Center for Surgical Science! We are looking for an experienced and dedicated #projectconsultant to lead the coordination of a #horizoneurope funding application within personalized medicine and support the administration of our current and future research projects.
Read more and apply before January 20, 2021.
https://centerforsurgicalscience.dk/projects-archive/project-consultant/

At the Center for Surgical Science (CSS) we are looking for an experienced and dedicated project consultant to lead the coordination of a Horizon Europe funding application within personalized medicine and support the administration of our current and future research projects. The position is limite...

🔥 Job opportunity: Please share with anyone who might be interested!The Center for Surgical Science (CSS) is looking for...
05/01/2021
Experienced Data Scientist | Center for Surgical Science (CSS)

🔥 Job opportunity: Please share with anyone who might be interested!

The Center for Surgical Science (CSS) is looking for an experienced #datascientist to join its amazing team of #personalizedmedicine professionals!

The position is offering multiple opportunities for #research, #innovation, and #personaldeveloment, focusing on the exploration of the #health #bigdata universe to provide first-time #bedside solutions.

Read more and apply before the 15th of January 2021.
https://centerforsurgicalscience.dk/projects-archive/data-scientist/

At the Center for Surgical Science (CSS) we are looking for a determined, proactive and experienced data scientist to join our Big Data & Personalized Medicine department and lead the data science operations.

Yesterday was reason for celebration as the last 2 of a total 100 patients were included in #INEXA, our triple blind, mu...
30/12/2020

Yesterday was reason for celebration as the last 2 of a total 100 patients were included in #INEXA, our triple blind, multicenter, randomized controlled trial comparing intracorporeal vs. extracorporeal anastomosis in minimally invasive right colectomy.
With primary outcome patient-reported postoperative recovery and secondary outcomes other measures of postoperative recovery, this #RCT aims to contribute with valuable high-level evidence on the best surgical practice in minimally invasive right colectomy in terms of postoperative recovery.

Many congratulations to PI Niclas van Dohrn and the surgical teams in Sjællands Universitetshospital, Køge and Herlev og Gentofte Hospital !
From Region Sjælland:
Ismail Gögenur Michael Seiersen Steffen Brisling Jens Ravn Eriksen Helin Yikilmaz Faisal Khesrawi
From Region Hovedstaden:
Mads Falk Klein Henrik Toft Andersen Jakob Lykke Frederik Bjerg Clausen Magnus Lauersen

At the Center for Surgical Science we are dedicated in examining innovative interventions before, during and after surge...
18/11/2020
Open Positions | Center for Surgical Science (CSS)

At the Center for Surgical Science we are dedicated in examining innovative interventions before, during and after surgery. We are currently looking to recruit two PhD students to conduct research in: surgical oncology and robot-assisted surgery and optimization of perioperative assessment of tissue perfusion.
If you would like to lead ambitious research projects and make a difference by shaping the treatments of the future, read more and apply before December 1, 2020.
We look forward to hearing from you!
#phdstudent #phdposition #surgicaloncology #research #robotsurgery #perfusion
https://centerforsurgicalscience.dk/job/

Open position for a PhD student to conduct research in robot-assisted surgery and optimization of perioperative assessment of tissue perfusion. See the job posting Open position for a PhD student in Surgical Oncology. See the job posting Open position for two medical students for research in cancer....

We are looking for a research technician/ lab technician to help with the daily operation of our newly established resea...
05/11/2020
Forskningsbioanalytiker/ laborant | Center for Surgical Science (CSS)

We are looking for a research technician/ lab technician to help with the daily operation of our newly established research lab, work on the cultivation of cell lines and organoid models, perform analyses and support our researchers with the lab work in their projects.
This is a full-time position, with start date in January 2021 or asap thereafter.
Application deadline: 15 November 2020
Sounds interesting? Click here for more info:
https://centerforsurgicalscience.dk/projects-archive/forskningsbioanalytiker-laborant/

Center for Surgical Science (CSS) søger en forskningsbioanalytiker/laborant til den daglige drift af et kirurgisk forskningslaboratorium.

Nordighealth
30/10/2020

Nordighealth

NorDigHealth bliver evalueret
I eftermiddag finder den obligatoriske evaluering af forskningsprojektet NorDigHealth sted – årsagen er, at vi er halvvejs igennem projektperioden. Det er konsulentfirmaet Kienbaum, som står for evalueringen, og fokus er bl.a. på fremdriften i projektet og samarbejdet mellem projektpartnerne.

#eu #interreg #nordighealth #kienbaum

NorDigHealth wird evaluiert.
Heute Nachmittag findet die obligatorische Evaluierung des Forschungsprojektes NorDigHealth statt. Ursache: Wir sind halbwegs im Projekt. Das Beratungshaus Kienbaum ist für die Evaluierung zuständig, und die Schwerpunkte sind u.a. die Fortschritte im Projekt und die Zusammenarbeit der Projektpartner.

Nordighealth
30/10/2020

Nordighealth

🇩🇰Generalforsamlingen for NorDigHealth er i gang. Projektets partnere er både mødt op fysisk og digitalt i lokalerne på Sjællands Universitetshospital.

#eu #interreg #nordighealth

🇩🇪Die Generalversammlung von NorDigHealth läuft. Die Projektpartner sind sowohl physisch als auch digital anwesend am Universitätsklinikum Seeland in Køge.

Receiving the influenza vaccine within 6 months after curative surgery for solid cancers, is associated to better outcom...
28/10/2020
The influenza vaccine - an old friend in new territories | Center for Surgical Science (CSS)

Receiving the influenza vaccine within 6 months after curative surgery for solid cancers, is associated to better outcomes according to a new nationwide register-based study. Read what Mikail Gögenur, the author of the paper, has to say about their exciting findings:
https://centerforsurgicalscience.dk/articles/the-influenza-vaccine/

Surgery is the only treatment that today can cure patients with colorectal cancer. However, up to 30% of patients experience a relapse of their cancer following curative-intended surgery. Relapse is the leading cause of death after cancer surgery, while a surgery-induced dysfunction in the immune sy...

We have an open position available for a #research #nurse. Do you know someone that might be interested? We'd love to he...
22/10/2020
Forskningssygeplejerske | Center for Surgical Science (CSS)

We have an open position available for a #research #nurse. Do you know someone that might be interested? We'd love to hear from them!
Application deadline: 01 November 2020
Position start: 01 January 2021
https://centerforsurgicalscience.dk/projects-archive/forskningssygeplejerske2020/

Center for Surgical Science på Sjællands Universitets Hospital Køge søger en medicinstuderende på kandidatdelen med interesse for akut mave-tarm kirurgi.

We are offering an exciting job opportunity to a talented medical student who will join the Nordighealth project and con...
12/08/2020
Medicinstuderende til forskning inden for akut mave-tarm kirurgi | Center for Surgical Science (CSS)

We are offering an exciting job opportunity to a talented medical student who will join the Nordighealth project and conduct research on the optimization of the postoperative course of patients who've had gastrointestinal emergency surgery with the use of #smartphones and #wearables.
Job start is September 1, 2020 (or asap thereafter) and the position is based at Sjællands Universitetshospital, Køge.

Are you curious to know what a research year is like? Visit: https://centerforsurgicalscience.dk/research-student-css/

Send in your application by August 20, 2020! https://centerforsurgicalscience.dk/projects-archive/job-052020b/

Center for Surgical Science på Sjællands Universitets Hospital Køge søger en medicinstuderende på kandidatdelen med interesse for akut mave-tarm kirurgi.

The Nordighealth projects are a big part of Region Zealand's Research Report for 2019. Congratulations and keep up the g...
22/06/2020

The Nordighealth projects are a big part of Region Zealand's Research Report for 2019. Congratulations and keep up the good work to all the researchers!
🥳🤩

🇩🇰Årsrapport om forskning udkommer.

Årets forskningsrapport fra #RegionSjælland er udkommet, og i den kan man læse om de forskellige forskningsprojekter, som udgør NorDigHealth. Man kan bl.a. læse om, hvordan Torben Lykke Sørensen og Anders Jürs arbejder på at gøre det muligt at opdage øjensygdommen AMD tidligt i sygdomsforløbet. Også Johan Clausens og Ismail Gögenurs forskning i overvågning af akut opererede patienter omtales. Vi finder også ud af, om interregudvalgsmedlem og forsøgsdeltager #FreddyBlak er blevet mere motiveret til at dyrke motion af at have en skridttæller på håndleddet.

Vi kommer til at skrive mere om forskningsrapporten og studierne i NorDigHealth hen over sommeren, både her og på vores hjemmeside: www.nordighealth.eu

#interreg #eu

🇩🇪Forschungsbilanz der Region Seeland erscheint.

Die Forschungsbilanz dieses Jahres der Region Seeland ist erschienen, und darin kann man mehr über die verschiedenen Forschungsprojekte erfahren, die NorDigHealth ausmachen. U.A. erfahren die Leser, wie Prof. Torben Lykke Sørensen und Doktorand Anders Jürs versuchen, die Augenkrankheit AMD so früh wie möglich zu entdecken. Auch die Forschung von Prof. Ismail Gögenur und Doktorand Johan Clausen in der Überwachung von akut operierten Patienten wird beschrieben. Wir erfahren auch, ob Interregausschussmitglied und Testteilnehmer Freddy Blak aktiver ist, wenn er einen Schrittzähler trägt.

Wir werden über den Sommer mehr über die Forschungsbilanz und die Studien in NorDigHealth schreiben. Sie können uns sowohl hier folgen als auch auf unserer Webseite: www.nordighealth.eu.

25/05/2020
Nordighealth

Discover our research study about how the use of wearables can track complications after high-risk surgery. The study is part of the Danish-German Nordighealth health project that aims to improve health and prevent disease through the use of new digital technology.

🇩🇰”Wearables” forebygger komplikationer efter højrisikokirurgi
Ismail Gögenur, professor, overlæge og dr. med. ved Kirurgisk Afdeling på Sjællands Universitetshospital, leder den del af NorDigHealths studier, der arbejder med forebyggelse af komplikationer ved højrisikokirurgi, og han har fokus på nye kirurgiske behandlinger. I magasinet Medicoteknik under temaet ”Kunstig intelligens i sundhedens tjeneste” 🤖👨‍⚕️ skriver han om de såkaldte ”wearables” – små apparater, der måler patientens vitale funktioner efter operation og udskrivelse, og som kan forebygge genindlæggelser og alvorlige komplikationer ⌚️📲

Ph.d. Johan Clausen arbejder sammen med Ismail Gögenur med studiet, og de to forskere beskæftiger sig særligt med mave-tarm-kirurgiske patienter. Højrisikokirurgien på det område er eksempelvis operationer på patienter med tarmslyng, hvor afføringen ikke kan passere tarmsystemet, eller patienter med hul på tarmen. Ofte vil problemet og behovet for operation opstå akut, og det stresser patienten yderligere, forklarer Ismail Gögenur i artiklen.

Efter operationen har patienterne større risiko for at udvikle komplikationer, der kan medføre genindlæggelse – og i værste fald døden. Her kommer udviklingen af digitale metoder til at overvåge patienternes fysiologiske tilstand ind og hjælper med at forstå og forebygge komplikationerne. Patienterne udskrives med wearables, som løbende monitorerer patienternes vitale funktioner: Aktivitet, bevægelse, søvnrytme, hjerterytme, vejrtrækning og blodsukkerniveau. Disse data kombineret med maskinlæringsalgoritmer (kunstig intelligens), der analyserer dem, viser stort potentiale for at forudsige komplikationer, inden de bliver livstruende, skriver Ismail Gögenur.

Første skridt i den slags analyser er at monitorere en stadig større gruppe af patienter, så algoritmerne kan udvikles til at spore komplikationerne. Sideløbende udvikler man kliniske systemer, så læger og sundhedspersonale kan handle på de første tegn på komplikationer. NorDigHealth-studiet er et af forskningsstudierne, hvor der arbejdes med det. På sigt er der både menneskelige og økonomiske gevinster gevinster for patienter og sundhedssystemet ved at forebygge og undgå komplikationer og genindlæggelser.

Læs hele Ismail Gögenurs artikel i Medicoteknik på NorDigHealths hjemmeside:
https://www.nordighealth.eu/detalje-nyheder/wearables-forebygger-komplikationer-efter-h%C3%B8jrisikokirurgi

🇩🇪 ”Wearables” verhindern Komplikationen nach einer OP mit hohem Risiko
Prof. Dr. Ismail Gögenur ist Chefarzt der chirurgischen Abteilung des Universitätsklinikum Seeland und leitet den Teil der Studien von NorDigHealth, die sich mit der Vorbeugung von Komplikationen bei Operationen mit hohem Risiko befassen, und konzentriert sich auf neue chirurgische Behandlungen. In der dänischen Zeitschrift Medicoteknik unter dem Thema "Künstliche Intelligenz im Gesundheitswesen" 🤖👨‍⚕️ schreibt er über die sogenannten "Wearables" - kleine Geräte, die die Vitalfunktionen des Patienten nach Operation und Entlassung messen und Neuaufnahmen und schwerwiegende Komplikationen verhindern können ⌚️📲

PhD Johan Clausen arbeitet mit Ismail Gögenur an der Studie, und die beiden Forscher befassen sich hauptsächlich mit Patienten die Magen-Darm-Chirurgie benötigen. Bei der Hochrisikochirurgie in diesem Bereich handelt es sich beispielsweise um Operationen bei Patienten mit Darmverschluss, bei denen der Stuhl nicht durch den Darmtrakt kommen kann, oder bei Patienten mit Darmperforation. Oft treten das Problem und die Notwendigkeit einer Operation dringend auf, und dies wird den Patienten weiter belasten, erklärt Ismail Gögenur in dem Artikel.

Nach der Operation besteht für Patienten ein höheres Risiko, Komplikationen zu entwickeln, die zu einer erneuten Aufnahme führen können - und im schlimmsten Fall zum Tod. Hier kommt die Entwicklung digitaler Methoden zur Überwachung des physiologischen Zustands der Patienten und hilft, die Komplikationen zu verstehen und zu verhindern. Die Patienten werden mit Wearables entlassen, die die Vitalfunktionen der Patienten kontinuierlich überwachen: Aktivität, Bewegung, Schlafrhythmus, Herzschlag, Atmung und Blutzuckerspiegel. Diese Daten, kombiniert mit Algorithmen für maschinelles Lernen (künstliche Intelligenz), die sie analysieren, zeigen ein großes Potenzial für die Vorhersage von Komplikationen, bevor sie lebensbedrohlich werden, schreibt Ismail Gögenur.

Der erste Schritt bei dieser Art der Analyse besteht darin, eine ständig wachsende Gruppe von Patienten zu überwachen, damit die Algorithmen entwickelt werden können, um die Komplikationen zu verfolgen. Parallel dazu werden klinische Systeme entwickelt, damit Ärzte und Krankenhauspersonal auf die ersten Anzeichen von Komplikationen reagieren können. Die NorDigHealth-Studie ist eine der Forschungsstudien, die damit arbeiten. Langfristig kommen sowohl menschliche als auch finanzielle Belohnungen den Patienten und dem Gesundheitssystem zugute, indem Komplikationen und Wiederaufnahmen verhindert und vermieden werden.

Lesen Sie den gesamten Artikel von Ismail Gögenur in Medicoteknik (in dänisch) auf der Homepage von NorDigHealth:
https://www.nordighealth.eu/nachrichtendetail/kleinger%C3%A4te-verhindern-komplikationen-nach-einer-operation

#nordighealth #interreg #eu #sundhedsteknologi #gesundheitstechnologie #suh #medicoteknik #ai
Interreg Deutschland-Danmark Heino Knudsen

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Researching ways to reduce stress in surgical procedures

The Center for Surgical Science was founded in 2015 to research the physiological changes caused by a surgical procedure.

It is generally acknowledged that even small surgical procedures can affect the patients’ sickness and mortality rates after an operation. A lot of focus has been put in recent years on finding ways to reduce physiological stress in relation to surgery, so that patients experience pain, fatigue, heart problems, sleep disturbances, depressive symptoms and impaired immune response to a minimum degree.

One of our major research areas at CSS is the characterization of surgical stress associated with surgery. We investigate which genetic inflammatory, oxidative and immunological changes can follow a cancer surgery. This knowledge will later be the basis for a “proof-of-concept” study about short-term preoperative treatment with immunosuppressive or anti-flammatory medication.

We also have studies on benign surgery, where we research the different treatments in patients with hernia and the complications after hernia surgery.