10/23/2026
đź’Š Taking blood pressure medication? There are 2 combinations you need to know about.
Alex here, your Canadian pharmacist 🇨🇦
If you take lisinopril, losartan, ramipril, or valsartan, this is important.
⚠️ 1. NSAID pain relievers
Medications like Advil (ibuprofen), Aleve (naproxen), and diclofenac can increase your risk of kidney injury when combined with ACE inhibitors or ARBs.
The risk is even higher if you’re also taking a diuretic (water pill). This combination is known as the “triple whammy.”
⚠️ 2. Potassium supplements
These blood pressure medications can cause your body to retain potassium.
Adding potassium supplements without medical guidance can increase your risk of dangerously high potassium levels, which can affect your heart rhythm.
And don’t forget to check potassium-containing salt substitutes, too.
âś… The takeaway?
Just because something is available over the counter doesn’t mean it’s safe with your prescriptions.
Don’t stop your prescribed medications on your own. Check with your pharmacist or healthcare provider before adding pain relievers, supplements, or salt substitutes.
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