22/10/2026
Manic to depressive in 30 seconds..
PMDD (Premenstrual Dysphoric Disorder) is a severe, chronic, and debilitating form of premenstrual syndrome (PMS) Symptoms occur during the luteal phase (1 to 2 weeks before a period starts, typically after ovulation
It is not a simple hormone imbalance, but rather an abnormal brain sensitivity to natural fluctuations in estrogen, progesterone, and neurosteroids like allopregnanolone.
It is often more prevalent in neurodivergent women