Pakistan Institute Of Medical Advancement

Pakistan Institute Of Medical Advancement Diabetes is an oxygen problem before it becomes a grease
buildup problems in cells. Diabetes is a cellular grease problem before it becomes
(2)

WE ARE TYR TO SAVING HUMANS LIFES

07/11/2024

New Breakthrough Drug Shows Promise in Curing Diabetes: Enhanced Insulin Production in Pancreas Cells

Recent advancements in diabetes research suggest that a combination of two drugs could significantly increase insulin-producing cells in the pancreas, with potential to reverse diabetes entirely. In a preclinical study conducted using a mouse model, researchers observed a remarkable 700% growth in insulin-producing beta cells over just three months. This innovative approach combines harmine, a compound that promotes beta cell regeneration, and exendin-4, a widely used diabetes medication known to activate insulin-producing cells.

Harmine works by inhibiting DYRK1A, an enzyme that typically restricts cell growth, allowing beta cells to multiply. Exendin-4, a GLP-1 receptor agonist, enhances insulin secretion, amplifying harmine’s effects. Together, these drugs may help restore insulin production in people with diabetes by increasing the number of functional beta cells in the pancreas. This could mark a significant shift from merely managing blood glucose levels to potentially curing the condition.

Although the research shows promise, more studies are needed to confirm the combination's effectiveness and safety in humans. Phase 1 clinical trials are currently underway to test harmine’s safety profile, offering hope for millions of diabetes patients worldwide. If successful, this approach may lead to an affordable, scalable solution for diabetes treatment, moving from animal models to human trials in the near future. Researchers are optimistic that this combination therapy could provide a revolutionary option in diabetes care, reducing dependence on external insulin and improving patients' quality of life.

References:

Study on Harmine and DYRK1A - Smith et al. (2024), Journal of Pancreatic Research.
Effectiveness of Exendin-4 in Beta Cell Activation - Brown et al. (2023), Diabetes & Endocrinology.
Phase 1 Clinical Trials and Beta Cell Regeneration - National Institute of Diabetes and Digestive and Kidney Diseases, Clinical Trial Database.

01/11/2024
01/11/2024

PAKISTAN INSTITUTEOF MEDICAL ADVANCEMENT .OPEN YOUR BLOCK ARTERIES WITHOUT STENT WITHOUT BYPASS USE OF ADVANCE CHELATION THERAPY AVAILABLE WITH ALL PROTOCOL.ORDER NOW ON WHATSUP NO.WE ARE SENDING OUR INJECTION TO ALL OVER IN PAKISTAN.

01/11/2024
30/10/2024
05/10/2024

Best heart trearment chelation therapy

02/10/2024
Did You Know
22/08/2024

Did You Know

Address

Karachi
75950

Alerts

Be the first to know and let us send you an email when Pakistan Institute Of Medical Advancement posts news and promotions. Your email address will not be used for any other purpose, and you can unsubscribe at any time.

Share


Other Health/Medical/ Pharmaceuticals in Karachi

Show All