Uppsala Monitoring Centre

22/10/2026

How can time-to-onset (TTO) data support signal validation?

Using adverse event reports from VigiBase, Annette Rudolph, Monica Tarapues, Oskar Gauffin, and Qun-Ying Yue explored TTO patterns for four glomerular diseases following COVID-19 vaccination, considering both new-onset and relapse cases. Their findings show how reviewing and characterising TTO data can complement traditional disproportionality analysis during signal validation.

Read their study to find out more at the link below👇

Background Adverse event reports of glomerular diseases (GDs) following coronavirus disease 2019 (COVID-19) vaccination collected nationally have been shared to VigiBase, the global database of adverse event reports for medicines and vaccines. From literature reports, different GDs following COVID-1...

20/10/2026

Advancing the state of the art in duplicate detection in 📚

Duplicate adverse event reports in large-scale pharmacovigilance databases can distort statistical analyses and may mislead clinical assessments. Computational methods are essential for identifying duplicates at scale.

Jim Barrett, Nils Erlanson, Joana Félix, and Niklas Norén introduce a new predictive model, 2025, designed to identify duplicate reports involving drugs and vaccines with improved precision and recall. By leveraging predictive modeling, free-text information, and country-specific features, the model outperforms vigiMatch 2017 while remaining computationally efficient and explainable.

Read the article to discover more 👉 https://ai.jmir.org/2026/1/e95282

19/10/2026

Time-to-onset (TTO) is the time between the start of a medicine or vaccine of interest and the onset of a suspected adverse drug reaction (ADR) and can range from seconds to years. However, ADRs with a long TTO (≥6 months) can be challenging to assess and may go unrecognised.

UMC researchers explore TTO patterns in , with a special focus on long TTO, in a new poster.

Access it online to learn more 👉 https://ow.ly/Glpa50ZVShI

16/10/2026

🎥 Raising awareness of and digitalisation efforts with healthcare professionals and the public can improve reporting rates and help to strengthen reporting systems.

As part of their efforts to build a stronger reporting culture, the Therapeutics Information and Pharmacovigilance Centre (TIPC), part of the Namibia Medicines Regulatory Council (NMRC)🇳🇦, delivers sensitisation workshops across the country to encourage adverse event reporting.

Learn how these workshops deliver positive impact in health districts in the film below👇

Explore the rest of the 'WHO PIDM in Focus' series on YouTube 👉 ow.ly/j81o50QPVtJ

15/10/2026

Pharmacovigilance is not a one-size-fits-all science or profession. Career pathways span regulatory authorities, academia, and industry, drawing on people with diverse experiences to support worldwide. With so many options, how do you find your place?

In a new episode of , Myriam Salem and Francesco Salvo share their career stories, explain how encounters with patients and mentors inspired them to enter the field, and offer practical advice for those looking to break into .

🎧 Listen now 👉 https://ow.ly/PhIo50ZXa3Q

13/10/2026

Duplicate reports can make signal detection and validation more difficult. Although current screening methods can identify suspected duplicates at scale, false positives remain a challenge.

A new UMC research poster presents how a deterministic, probability-anchored system could support second-line assessment of suspected duplicate reports flagged by vigiMatch in .

Access the poster for more 👉 https://ow.ly/emC450ZX7Hm
Learn more about the method on our website 🌐 https://ow.ly/fuLv50ZX7Hp

12/10/2026

🎥 What does mean to you?

Each year, we partner with stakeholders around the world to raise awareness of and encourage the reporting of suspected side effects. We asked our colleagues in Egypt🇪🇬 to share their Med Safety Story and explain how ISoP Egypt's efforts have helped foster a stronger medicines safety culture.

Hadir Rostom, pharmacovigilance consultant and ISoP Online Advisory Board Member, shares how provides an opportunity to educate, engage, and empower in the film below👇

📆 Join us from 2–8 November for this year's campaign. Learn how you can get involved 👉 http://ow.ly/XEoc50LlhaJ

09/10/2026

Changes coming to UMC's learning platform 📢

We're excited to introduce UMC Learning, our new knowledge centre for medicines safety. From 19 October 2026, this new platform will streamline your learning experience and support evolving pharmacovigilance training needs.

To help you prepare for this transition, we've outlined key information on deadlines, accessibility, and learner-specific actions in the carousel below👇

Have questions? Find answers and support in our FAQ 👉 https://ow.ly/7zwi50ZWlZB

08/10/2026

Putting into practice 🌱

Mexico🇲🇽 is implementing new measures to integrate medication and medical device management and related waste streams. Through stricter controls on storage, transport, treatment, destruction, and documentation, the framework aims to reduce contamination of water, soil, and ecosystems while simultaneously limiting opportunities for medicine diversion, misuse, and illegal recycling.

Read up on Mexico's new pharmaceutical waste framework in at the link below👇

Mexico's new pharmaceutical waste framework puts One Health into practice, from hazardous-waste handling in hospitals to expired pills in the kitchen drawer.

07/10/2026

How can large language models (LLMs) help identify pregnancy-related reports when coded information is incomplete?

In a new poster, UMC researchers explore the potential of an to retrieve pregnancy-related reports that the pregnancy algorithm misses and extract relevant information from narratives.

🌐 Access the poster online to learn more 👉 ow.ly/Qr7W50ZUtUm

🎧 Listen to this episode for more on pregnancy-related pharmacovigilance 👉 ow.ly/bT8250VrmAK