Functional Dr Ho See Yunn

A page for updating on latest research and findings on medical and functional health to empower pati

17/09/2026

Just wrapped up an incredible longevity medicine conference last weekend—truly one of the most inspiring gatherings I’ve attended.

It was a privilege to connect with clinicians, researchers, biotech founders, and innovators all united by a shared mission: extending healthspan and redefining ageing.

Some standout moments:
- Hearing . Brian Kennedy (NUS) unpack the science behind the biological ageing clock and how we can measure—and potentially slow—ageing at the molecular level.
- Listening to Aubrey de Grey share his vision for the future of longevity medicine and damage-repair strategies.
- Engaging with researchers presenting cutting-edge work on autophagy and stem cell therapies for regeneration.

I also had the opportunity to visit gut health and stem cell companies in Shanghai, along with a dedicated longevity center,seeing firsthand how science is translating into real-world solutions.

Grateful for the chance to meet so many brilliant minds advancing this field. The future of longevity medicine is not just coming—it’s already being built.

GutHealth Healthspan Shanghai Innovation

20/08/2026

It was a true honor to meet my mentor, Dr. Thomas Rau, and his team during their visit to Thailand, including a visit to AMSEL Biohealth Center—an outstanding center dedicated to integrative and biological medicine for patients with chronic conditions.

Dr. Rau has always taught me one essential principle: first, address and optimize the cellular milieu. This foundational step helps patients feel better and creates the conditions in which other longevity and regenerative treatments can work more effectively.

16/08/2026

Lately quite a few of my patients who are on a keto diet or carnivorous diet were found to have very high LDL despite them being generally healthy. High LDL is not an urgent indication to start statins straight away as it may be dietary related. Instead, it is important to look at the risk factors of the patient from NMR lipid profile, apoB, lipoprotein (a) and even cardiovascular imaging to determine the risk of the patient before deciding on the next steps of the treatment.

In this blog article, I discuss why LDL usually shoots up in patients on a keto or canivorous diet and what are the risk factors who should be looking at that are more important to control to reduce the cardiovascular risk of the patient.

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See link in bio

06/08/2026

How Sleep Slows Biological Aging

Emerging research is now linking sleep directly with biological aging, not just chronological years. Sleep loss and disturbances appear to accelerate aging processes at the cellular and molecular levels.

Reviews of the literature conclude that poor sleep contributes to:
- Altered metabolism and increased oxidative stress
- Impaired repair and restoration mechanisms
- Telomere shortening and increased cellular senescence
- Accelerated epigenetic aging

Read more on the link in my bio on the steps to having good sleep for longevity.

Also check out the feature on SCMP on the link in my bio where I was quoted on a holistic approach to having good sleep.

03/08/2026

Targeting the Root of Inflammaging

Chronic, low-grade inflammation, often called inflammaging, is a shared driver of heart disease, neurodegeneration and accelerated biological aging. In 2026, USC researchers identified thymulin, a hormone produced by the thymus gland that declines with age, as the first naturally occurring substance shown to actively reverse this chronic inflammation in animal models.

The logic is simple: the thymus shrinks with age, thymulin falls, and inflammaging rises. If thymulin can be safely supplemented or pharmacologically boosted in humans, it could address the smoldering immune dysfunction sitting beneath multiple age-related diseases at once. The work is currently in mice, so human translation remains unconfirmed, but it reframes the thymus as a central lever in longevity.

Supporting the thymus remains the TRIIM approach — rhGH, DHEA and metformin produced a ~2.5-year epigenetic age reversal alongside MRI-confirmed thymic regeneration in the 2019 Aging Cell study. However TRIIM is the strongest existing proof that thymic regeneration is achievable in adult humans, but it is nine men, open-label, uncontrolled, not preregistered, and the intervention is rhGH — a materially different risk conversation than a peptide, particularly around IGF-1 and occult malignancy.

Inflammation is the common enemy. From thymulin to Advanced Glycation Endproduct-clearing enzymes, the most promising targets converge on reversing inflammaging for enhancing Longevity.

30/07/2026

Honored to be featured in this article breaking down what triggers inflammation, the concept of “inflammaging,” and the practical steps you can take to prevent it. Link in bio.

28/07/2026

Recently, I met a fellow practitioner’s son as a patient as his dad wanted to seek a more holistic approach to his son’s allergies problems. The 8 year old boy was suffering from allergic rhinitis for a long time and had turbinates surgery and was put on immunologics to suppress his frequent allergy flare-ups. But this immune suppression brought on frequent infections and he ended up having multiple courses of antibiotics. Upon further questioning, his diet was full of dairy products and his home environment was having mold issues but these were not dealt with in the first place. Dietary allergens had not been discussed to be a cause of his allergies.

In this article, I discuss the role of food allergies as a trigger cause of nasal allergies and why it is important to treat allergies from the root cause from the gut rather than overloading the body with immune suppressants and antibiotics without dealing with the gut in the first place. It is important to have a holistic approach to allergies.

Read more in the link to the article via the link in my bio.

18/07/2026

We are delighted to announce that Restore has been recognized among Tatler’s longevity clinics in Asia. Our clinic is dedicated to leveraging leading-edge innovation and advanced biomarker tracking to enhance both lifespan and healthspan for our patients, and we are deeply grateful for this recognition.

16/07/2026

What causes Inflammaging and how can we measure this?

I often can asked by patients what test are there to check for inflammation in the body. The usual blood biomarkers like CRP and ESR shows acute inflmamation but what tests are there to measure chronic low grade inflammation that may accelerate ageing?

In this article, I talk about what triggers chronic inflammation and also a test I recently came across called GlycanAge which can help with measuring chronic low grade inflammation even before ESR and CRP comes up.

Click on the link in bio read more.

13/07/2026

Today, I had the opportunity to discuss “Inflammation” and its impact on longevity during an interview.

It’s interesting to note that while we often focus on various anti-aging treatments, we rarely address the underlying process that drives aging: chronic inflammation.

Inflammaging refers to a silent, smoldering inflammation that accelerates aging from within. However, it is also a highly modifiable target in a modern longevity program.

In my article, I delve into what inflammaging is, how to recognize its signs, and practical steps you can take to cool the “inner fire” and extend your healthspan.

For those interested in early interventions to prevent inflammation from accelerating aging in your body, check out my article via the link in my bio.

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Room 1602, 16F, 1 Duddell Street
Bangkok

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http://www.thefmcollective.com/, http://Www.RestoreIntegrativeMedical.com/

แจ้งเตือน

เป็นคนแรกที่รู้ข่าว: เราจะส่งอีเมลแจ้งเมื่อ Functional Dr Ho See Yunn โพสต์ข่าวสารและโปรโมชั่น อีเมลของคุณจะไม่ถูกนำไปใช้เพื่อวัตถุประสงค์อื่น และคุณสามารถยกเลิกการรับข่าวสารได้ทุกเมื่อ

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