Epidemiology

Epidemiology Like EPIDEMIOLOGY to get the latest updates! EPIDEMIOLOGY publishes original research from all fields of epidemiology. The journal also welcomes review articles and meta-analyses, novel hypotheses, descriptions and applications of new methods, and discussions of research theory or public health policy.

We give special consideration to papers from developing countries.

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Recent Changes in the Patterns of Breast Cancer as a Proportion of All Deaths According to Race and Ethnicityfrom Trenth...
10/13/2021
Recent Changes in the Patterns of Breast Cancer as a... : Epidemiology

Recent Changes in the Patterns of Breast Cancer as a Proportion of All Deaths According to Race and Ethnicity

from Trentham-Dietz, Amy; Chapman, Christina Hunter; Bird, Jennifer; Gangnon, Ronald E.

. Methods: Using publicly available datasets (CDC WONDER, Human Mortality Database), we developed an age–period–cohort model of breast cancer mortality and breast cancer deaths as a proportion of all deaths during 1968–2019 among all women and by 5 race/ethnicity groups with sufficient numbers...

Spatial Errors in Automated Geocoding of Incident Locations in Australian Su***de Mortality Datafrom Torok, Michelle; Ko...
10/13/2021
Spatial Errors in Automated Geocoding of Incident Locations ... : Epidemiology

Spatial Errors in Automated Geocoding of Incident Locations in Australian Su***de Mortality Data

from Torok, Michelle; Konings, Paul; Passioura, Jason; Chen, Nicole A.; Hewett, Michael; Phillips, Matthew; Burnett, Alexander; Shand, Fiona; Christensen, Helen

extent to which common completeness and positional spatial errors are present in su***de data due to the underlying geocoding process. Methods: Using Australian su***de mortality data from the National Coronial Information System for the period of 2008–2017, we compared the custodian automated geo...

Estimating the Impact of Sustained Social Participation on Depressive Symptoms in Older Adultsfrom Shiba, Koichiro; Torr...
10/12/2021
Estimating the Impact of Sustained Social Participation on... : Epidemiology

Estimating the Impact of Sustained Social Participation on Depressive Symptoms in Older Adults

from Shiba, Koichiro; Torres, Jacqueline M.; Daoud, Adel; Inoue, Kosuke; Kanamori, Satoru; Tsuji, Taishi; Kamada, Masamitsu; Kondo, Katsunori; Kawachi, Ichiro

nterventions in social participation on subsequent depressive symptoms among older adults. Methods: Data were from a nationwide prospective cohort study of Japanese older adults ≥65 years of age (n = 32,748). We analyzed social participation (1) as a baseline exposure from 2010 (approximating a on...

Poverty, Deprivation, and Mortality Risk Among Women With HIV in the United Statesfrom Edmonds, Andrew; Breskin, Alexand...
10/12/2021
Poverty, Deprivation, and Mortality Risk Among Women With... : Epidemiology

Poverty, Deprivation, and Mortality Risk Among Women With HIV in the United States

from Edmonds, Andrew; Breskin, Alexander; Cole, Stephen R.; Westreich, Daniel; Ramirez, Catalina; Cocohoba, Jennifer; Wingood, Gina; Cohen, Mardge H.; Golub, Elizabeth T.; Kassaye, Seble G.; Metsch, Lisa R.; Sharma, Anjali; Konkle-Parker, Deborah; Wilson, Tracey E.; Adimora, Adaora A.

conomic context among participants of the Women’s Interagency HIV Study. Methods: Starting in October 2013, we linked geocoded residential census block groups to the 2015 Area Deprivation Index (ADI) and two 2012–2016 American Community Survey poverty variables, categorized into national tertile...

Prescription Opioid Laws and Opioid Dispensing in US Counties: Identifying Salient Law Provisions With Machine Learningf...
10/11/2021
Prescription Opioid Laws and Opioid Dispensing in US... : Epidemiology

Prescription Opioid Laws and Opioid Dispensing in US Counties: Identifying Salient Law Provisions With Machine Learning

from Martins, Silvia S.; Bruzelius, Emilie; Stingone, Jeanette A.; Wheeler-Martin, Katherine; Akbarnejad, Hanane; Mauro, Christine M.; Marziali, Megan E.; Samples, Hillary; Crystal, Stephen; Davis, Corey S.; Rudolph, Kara E.; Keyes, Katherine M.; Hasin, Deborah S.; Cerdá, Magdalena

chine-learning approach to identify salient law provisions and combinations associated with dispensing rates to test in future research. Methods: Using 162 prescription opioid law provisions capturing prescription drug monitoring program (PDMP) access, reporting and administration features, pain man...

A New Approach for Classifying Fetal Growth Restrictionfrom Hutcheon, Jennifer A.; Riddell, Corinne A.; Himes, Katherine...
10/11/2021
A New Approach for Classifying Fetal Growth Restriction : Epidemiology

A New Approach for Classifying Fetal Growth Restriction

from Hutcheon, Jennifer A.; Riddell, Corinne A.; Himes, Katherine P.

for identifying fetal growth restriction at birth that combines information on multiple, imperfect measures of fetal growth restriction in a probabilistic manner. Methods: We combined information on birthweight, placental weight, placental malperfusion lesions, maternal disease, and fetal acidemia u...

Validation of a Claims-based Algorithm to Identify Pregestational Diabetes Among Pregnant Women in the United Statesfrom...
10/08/2021
Validation of a Claims-based Algorithm to Identify... : Epidemiology

Validation of a Claims-based Algorithm to Identify Pregestational Diabetes Among Pregnant Women in the United States

from Wood, Mollie E.; Chen, Szu-Ta; Huybrechts, Krista F.; Bateman, Brian T.; Gray, Kathryn J.; Seely, Ellen W.; Zhu, Yanmin; Mogun, Helen; Patorno, Elisabetta; Hernández-Díaz, Sonia

evaluate the validity of an administrative claims-based algorithm to identify pregestational diabetes. Methods: Using a cohort of pregnant women nested within the Medicaid Analytic Extract (MAX) database, we developed an algorithm to identify pregestational type 1 and type 2 diabetes, distinct from....

Detecting Heterogeneity of Intervention Effects Using Analysis and Meta-analysis of Differences in Variance Between Tria...
10/08/2021
Detecting Heterogeneity of Intervention Effects Using... : Epidemiology

Detecting Heterogeneity of Intervention Effects Using Analysis and Meta-analysis of Differences in Variance Between Trial Arms

from Mills, Harriet L.; Higgins, Julian P.T.; Morris, Richard W.; Kessler, David; Heron, Jon; Wiles, Nicola; Davey Smith, George; Tilling, Kate

ty is lower than the power to detect the same size of main effect. Methods: We describe several methods for assessing differences in variance in trial arms and apply them to a single trial with individual patient data and to meta-analyses using summary data. Where individual data are available, we u...

Marginal Sufficient Component Cause Model: An Emerging Causal Model With Merits?from Suzuki, Etsuji; Yamamoto, Eiji
10/07/2021
Marginal Sufficient Component Cause Model: An Emerging... : Epidemiology

Marginal Sufficient Component Cause Model: An Emerging Causal Model With Merits?

from Suzuki, Etsuji; Yamamoto, Eiji

cause model—was proposed and applied in the context of interaction or mediation. The proponents of this model have emphasized its utility in visualizing the presence of “agonism” (a subtype of mechanistic interaction) in the counterfactual framework, claiming that the concept of agonism has no...

The Case Time Series Designfrom Gasparrini, Antonio
10/07/2021
The Case Time Series Design : Epidemiology

The Case Time Series Design

from Gasparrini, Antonio

using traditional studies, they require innovative analytical approaches. Here we present a new study design, called case time series, for epidemiologic investigations of transient health risks associated with time-varying exposures. This design combines a longitudinal structure and flexible control...

Estimating Vaccine Efficacy Against Transmission via Effect on Viral Loadfrom Kennedy-Shaffer, Lee; Kahn, Rebecca; Lipsi...
10/06/2021
Estimating Vaccine Efficacy Against Transmission via Effect ... : Epidemiology

Estimating Vaccine Efficacy Against Transmission via Effect on Viral Load

from Kennedy-Shaffer, Lee; Kahn, Rebecca; Lipsitch, Marc

including efficacy against transmission of different viral variants, will help model epidemic trajectory and determine appropriate control measures. Recent studies have proposed using random virologic testing in individual randomized controlled trials to improve estimation of vaccine efficacy agains...

Antigen-based Rapid Diagnostic Testing or Alternatives for Diagnosis of Symptomatic COVID-19: A Simulation-based Net Ben...
10/06/2021
Antigen-based Rapid Diagnostic Testing or Alternatives for... : Epidemiology

Antigen-based Rapid Diagnostic Testing or Alternatives for Diagnosis of Symptomatic COVID-19: A Simulation-based Net Benefit Analysis

from Kendall, Emily A.; Arinaminpathy, Nimalan; Sacks, Jilian A.; Manabe, Yukari C.; Dittrich, Sabine; Schumacher, Samuel G.; Dowdy, David W.

inical judgment alone for diagnosing symptomatic COVID-19 in an outpatient setting (10% COVID-19 prevalence among the patients tested, 3-day PCR turnaround) and a hospital setting (40% prevalence, 24-hour PCR turnaround). We simulated transmission from cases and contacts, and relationships between t...

Effect of Adjustment for Case Misclassification and Infection Date Uncertainty on Estimates of COVID-19 Effective Reprod...
10/06/2021
Effect of Adjustment for Case Misclassification and... : Epidemiology

Effect of Adjustment for Case Misclassification and Infection Date Uncertainty on Estimates of COVID-19 Effective Reproduction Number

from Goldstein, Neal D.; Quick, Harrison; Burstyn, Igor

veillance data from the Colorado Department of Public Health & Environment by report and illness onset dates for 9 March 2020 to 30 September 2020. We used existing Bayesian methods to first adjust for misclassification in testing and surveillance, followed by deconvolution of date of infection. We....

SARS-CoV-2: An Empirical Investigation of Rose’s Population-based Logicfrom Bruckner, Tim; Das, Abhery; Singh, Parvati; ...
10/05/2021
SARS-CoV-2: An Empirical Investigation of Rose’s... : Epidemiology

SARS-CoV-2: An Empirical Investigation of Rose’s Population-based Logic

from Bruckner, Tim; Das, Abhery; Singh, Parvati; Boden-Albala, Bernadette

is logic applies to SARS-CoV-2 infected persons considered low to moderate risk. Methods: We conducted a population-representative survey and sero-surveillance study for SARS-CoV-2 among adults in Orange County, California. Participants answered questions about health behaviors and provided a finger...

Routine Hospital-based SARS-CoV-2 Testing Outperforms State-based Data in Predicting Clinical Burdenfrom Covello, Leonar...
10/05/2021
Routine Hospital-based SARS-CoV-2 Testing Outperforms... : Epidemiology

Routine Hospital-based SARS-CoV-2 Testing Outperforms State-based Data in Predicting Clinical Burden

from Covello, Leonard; Gelman, Andrew; Si, Yajuan; Wang, Siquan

e actual viral incidence in the community and as predictors of clinical burden. In the absence of any successful public or academic campaign for comprehensive or random testing, we have developed a proxy method for synthetic random sampling, based on viral RNA testing of patients who present for ele...

Air Pollution and Autism Spectrum Disorder in Israel: A Negative Control Analysisfrom Magen-Molho, Hadas; Weisskopf, Mar...
10/05/2021
Air Pollution and Autism Spectrum Disorder in Israel: A... : Epidemiology

Air Pollution and Autism Spectrum Disorder in Israel: A Negative Control Analysis

from Magen-Molho, Hadas; Weisskopf, Marc G.; Nevo, Daniel; Shtein, Alexandra; Chen, Shimon; Broday, David; Kloog, Itai; Levine, Hagai; Pinto, Ofir; Raz, Raanan

ntrol study included all children diagnosed with ASD (detected through 31 December 2016) born during 2007–2012 in Israel and residing in the study area (N = 3,843), and matched controls of the same age (N = 38,430). We assigned individual house-level exposure estimates for each child. We estimated...

Neighborhood Walkability and Mortality in a Prospective Cohort of Womenfrom India-Aldana, Sandra; Rundle, Andrew G.; Zel...
10/04/2021
Neighborhood Walkability and Mortality in a Prospective... : Epidemiology

Neighborhood Walkability and Mortality in a Prospective Cohort of Women

from India-Aldana, Sandra; Rundle, Andrew G.; Zeleniuch-Jacquotte, Anne; Quinn, James W.; Kim, Byoungjun; Afanasyeva, Yelena; Clendenen, Tess V.; Koenig, Karen L.; Liu, Mengling; Neckerman, Kathryn M.; Thorpe, Lorna E.; Chen, Yu

nt and Health Neighborhood Walkability Index (BEH-NWI) for each participant circa 1990. The participants were recruited from 1985 to 1991 in New York City and followed for an average of 27 years. We conducted survival analyses using Cox proportional hazards models to assess the association between n...

Risk of serious infection with low-dose glucocorticoids in patients with rheumatoid arthritis: an instrumental variable ...
09/28/2021
Risk of serious infection with low-dose glucocorticoids in... : Epidemiology

Risk of serious infection with low-dose glucocorticoids in patients with rheumatoid arthritis: an instrumental variable analysis

from George, Michael D.; Hsu, Jesse Y.; Hennessy, Sean; Chen, Lang; Xie, Fenglong; Curtis, Jeffrey R.; Baker, Joshua F.

s with RA on stable immunomodulatory therapy for >6 months receiving no glucocorticoids or ≤5mg/day using Medicare data from 2006-2015. We used provider preference for glucocorticoids as an instrumental variable (IV) to assess associations between low-dose glucocorticoid use and risk of infection ...

The Role of Childhood Asthma in Obesity Development: A Nationwide U.S. Multi-cohort Studyfrom
09/27/2021
The Role of Childhood Asthma in Obesity Development: A... : Epidemiology

The Role of Childhood Asthma in Obesity Development: A Nationwide U.S. Multi-cohort Study

from

udied 8716 children between ages 6-18.5 years who were non-obese at study entry participating in 18 U.S. cohorts of the Environmental influences on Child Health Outcomes program (among 7299 children with complete covariate data mean [SD] study entry age=7.2 [1.6] years and follow-up=5.3 [3.1] years)...

Accounting for Preinvasive Conditions in Analysis of Invasive Cancer Risk: Application to Breast Cancerfrom Kim, Jung In...
09/27/2021
Accounting for Preinvasive Conditions in Analysis of... : Epidemiology

Accounting for Preinvasive Conditions in Analysis of Invasive Cancer Risk: Application to Breast Cancer

from Kim, Jung In; Fine, Jason P.; Sandler, Dale P.; Zhao, Shanshan

omposite outcome could both lead to bias. Methods: We propose two solutions: one that provides exact estimates of risk based on distributional assumptions about progression, and one that provides risk bounds corresponding to extreme cases of no or complete progression. We compare these approaches th...

Observed Versus Expected COVID-19 Infections Among National Football League Players During the 2020 Seasonfrom Lopez, Mi...
09/13/2021
Observed Versus Expected COVID-19 Infections Among National ... : Epidemiology

Observed Versus Expected COVID-19 Infections Among National Football League Players During the 2020 Season

from Lopez, Michael J.; Mack, Christina; Bliss, Thompson; Wasserman, Erin B.; Myers, Emily; Solomon, Gary; Lynch, John; Casolaro, Anthony; Osterholm, Michael; Hanfling, Dan; Mayer, Thom; Sills, Allen K.

ason games and several thousand meetings and practices. In parallel, community cases of COVID-19 were highly prevalent. We assess the risk of holding a 2020 NFL season by comparing community and player COVID-19 infections. Methods: We used county-level COVID-19 test data from each team to establish....

Estimating vaccine efficacy against transmission via effect on viral loadfrom Kennedy-Shaffer, Lee; Kahn, Rebecca; Lipsi...
09/09/2021
Estimating vaccine efficacy against transmission via effect ... : Epidemiology

Estimating vaccine efficacy against transmission via effect on viral load

from Kennedy-Shaffer, Lee; Kahn, Rebecca; Lipsitch, Marc

including efficacy against transmission of different viral variants, will help model epidemic trajectory and determine appropriate control measures. Recent studies have proposed using random virologic testing in individual randomized controlled trials to improve estimation of vaccine efficacy agains...

09/08/2021
journals.lww.com

Dr. Danielle R. Gartner presents a video abstract for her article, “Integrating Surveillance Data to Estimate Race/Ethnicity-specific Hysterectomy Inequalities Among Reproductive-aged Women Who’s at Risk?”

from Danielle R. Gartner

09/07/2021
journals.lww.com

Dr. Emmanuel Stamatakis presents a video abstract for his article, “Is Cohort Representativeness Passé? Poststratified Associations of Lifestyle Risk Factors with Mortality in the UK Biobank”

from Emmanuel Stamatakis

09/06/2021
journals.lww.com

Dr. John Jackson presents a video abstract for his article, “Meaningful Causal Decompositions in Health Equity Research: Definition, Identification, and Estimation Through a Weighting Framework”

from John Jackson

09/06/2021
journals.lww.com

Dr. Joan Casey presents a video abstract for her article, “Trends from 2008 to 2018 in Electricity-dependent Durable Medical Equipment Rentals and Sociodemographic Disparities”

from Joan Casey

09/03/2021
journals.lww.com

Dr. Amir Sarayani presents a video abstract for his article, “A Pharmacoepidemiologic Approach to Evaluate Real-world Effectiveness of Hormonal Contraceptives in the Presence of Drug–drug Interactions”

from Amir Sarayani

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Patient centered¡¡
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I have worked in Viral Epidemiology with animal models and I feel I could carry out experiments to find out up how Coronavirus is being transmitted. We really know very little about how the virus moves from one person to another. What do you think?
When will Covid-19 antibody tests, which screen for whether someone has recovered from the disease, be available to the public?
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Articloe that may be of interest: To Battle the Coronavirus and Future Pandemic Threats We Must Have a 'Manhattan Project' NOW!