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Successful block at the sacral level should be confirmed with several complementary findings. Correct needle placement d...
10/19/2026

Successful block at the sacral level should be confirmed with several complementary findings. Correct needle placement does not always guarantee adequate anesthesia because local anesthetic may spread unevenly or fail to reach the intended sacral nerve roots.

How needle position, injectate spread, sensory testing, and motor assessment together help confirm a successful block at the sacral level.

Intraoperative blood pressure (BP) monitoring is a fundamental component of anesthetic care, providing clinicians with i...
09/23/2026

Intraoperative blood pressure (BP) monitoring is a fundamental component of anesthetic care, providing clinicians with information about circulatory stability and allowing prompt recognition and treatment of hypotension or hypertension.

For patients undergoing surgery without an arterial catheter, automated noninvasive intermittent blood pressure (NIBP) monitoring is...

Epidural anesthesia, a form of neuraxial anesthesia, is a cornerstone of both postoperative and labor pain management. I...
08/18/2026

Epidural anesthesia, a form of neuraxial anesthesia, is a cornerstone of both postoperative and labor pain management. It is frequently utilized for obstetric labor analgesia and for thoracic, intra-abdominal, and spinal surgical procedures that can be performed without muscle relaxation.

A second complication of prolonged epidural catheter use is the gradual shift of catheter tip positioning, which may compromise the...

The Controlled Substances Act (CSA) establishes five schedules for drug control based on a substance's medical utility, ...
07/13/2026

The Controlled Substances Act (CSA) establishes five schedules for drug control based on a substance's medical utility, safety profile, and potential for abuse.

The schedule classification of these drugs creates a complex balance between preventing substance abuse risk and advancing medical...

Because many chronic pain conditions remain difficult to treat with existing therapies, researchers have begun exploring...
06/09/2026

Because many chronic pain conditions remain difficult to treat with existing therapies, researchers have begun exploring the potential use of gene therapy in pain medicine.

Because many chronic pain conditions remain difficult to treat, researchers have begun exploring the use of gene therapy in pain medicine...

As a primary driver of cardiovascular morbidity and mortality, perioperative tachycardia represents a significant clinic...
05/05/2026

As a primary driver of cardiovascular morbidity and mortality, perioperative tachycardia represents a significant clinical challenge that requires careful management.

As a primary driver of cardiovascular mortality, perioperative tachycardia represents a clinical challenge requiring careful management. The physiological...

EGD is generally performed under moderate or deep sedation to improve patient comfort and procedural tolerance. However,...
04/07/2026

EGD is generally performed under moderate or deep sedation to improve patient comfort and procedural tolerance. However, in certain settings, EGD can be performed without systemic sedation. This approach primarily relies on topical anesthesia and careful patient selection.

One of the main benefits of performing EGD without sedation is a reduction in the risk of respiratory depression, hypotension, and adverse...

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400 Renaissance Center, Suite 2600
Detroit, MI
48243

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