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Do Nutrition Dave Okupniak, MS CNS, has over 30 years of experience helping people of all fitness levels achieve their wellness goals.

Exercise and CancerPhysical activity has been associated with lower risks of breast and colorectal cancer in epidemiolog...
10/19/2026

Exercise and Cancer

Physical activity has been associated with lower risks of breast and colorectal cancer in epidemiological studies; however, it has been unknown if these associations are actually causal or just coincidence.
Researchers analyzed genetic data from the UK Biobank and the Genome-Wide Association (GWA) consortia, a collaborative, large-scale scientific network formed by international research groups to combine genetic data across tens of thousands or millions of individuals.
Their results support a potentially causal relationship between higher physical activity levels and lower risks of breast cancer and colorectal cancer. Based on these data, the promotion of physical activity is probably an effective strategy in the primary prevention of these commonly diagnosed cancers.
Nat Commun 2020 Jan 30;11(1):597. doi: 10.1038/s41467-020-14389-8.
Physical activity and risks of breast and colorectal cancer: a Mendelian randomization analysis
https://pubmed.ncbi.nlm.nih.gov/32001714/

Fiber decreases pre- and post-menopausal breast cancersIn this review of 19 studies covering 1,994,910 pre- and post-men...
10/12/2026

Fiber decreases pre- and post-menopausal breast cancers

In this review of 19 studies covering 1,994,910 pre- and post-menopausal women, total fiber in the diet was linked to an 8 percent decrease in the likelihood of developing breast cancer. Soluble fiber reduced chances by 10 percent, and insoluble fiber appeared to reduce chances by 7 percent.
Discussing the findings, Harvard University epidemiological research scientist, Maryam S. Farvid, PhD, said, “Our study contributes to the evidence that lifestyle factors, such as modifiable dietary practices, may affect chances of breast cancer. Our findings provide research evidence supporting the American Cancer Society dietary guidelines, emphasizing the importance of a diet rich in fiber, including fruits, vegetables, and whole grains.”

Reference: ACS Cancer Journal; 2020, 32816

Resveratrol and fiber improve life and health during menopauseResveratrol reduces pain, improves QOL in menopauseDoctors...
10/05/2026

Resveratrol and fiber improve life and health during menopause

Resveratrol reduces pain, improves QOL in menopause
Doctors think some of the discomforts of menopause come from declining levels of estrogen. In two earlier, shorter studies, resveratrol—a phytoestrogen—improved pain and feelings of well-being in postmenopausal women. In this longer-term third arm of the study, 125 healthy postmenopausal women took a placebo or 75 mg of resveratrol twice daily, in alternating, 12-month phases.
Compared to the placebo phase, during the resveratrol phase, women reported 18 percent less pain from age-related osteoarthritis and improved quality of life.
Commenting on the findings, doctors said “Within the same study, we observed fewer hot flushes, night sweats, heart discomfort, sleep problems, and muscle and joint discomfort with resveratrol. Although we don’t know the cause of chronic pain in postmenopause, we believe declining estrogen levels may be a factor.”

Reference: Menopause; 2020, Vol. 28, No. 1, 40-9

Note from Dave; While red and purple grapes as well as peanuts are good food sources of resveratrol and fiber, you would have to eat an enormous ammount to get the amount of resveratrol used in this study.
As always, please consult your physician before taking supplements, especially if you are on medications.

Sulforaphane improved processing speed, memoryEarlier studies found cruciferous vegetables such as broccoli, cabbage, ca...
09/28/2026

Sulforaphane improved processing speed, memory

Earlier studies found cruciferous vegetables such as broccoli, cabbage, cauliflower, and kale increased brain processing speed. These plants contain sulforaphane, a powerful antioxidant and anti-inflammatory.
In this study, doctors asked half of 144 healthy adults, average age 68, to take training exercises for the aging brain along with a placebo or sulforaphane; and asked the other half to play the 1984 tile-matching video game, Tetris, along with a placebo or sulforaphane.
While there was no improvement in the placebo/Tetris group, those that got aging-brain training—with placebo or sulforaphane—saw significant improvement in brain processing speed. Those taking sulforaphane—with placebo or brain training—in addition to improved brain-processing speed saw significant enhancements in working memory.
Doctors attribute the improvements in processing speed and working memory to the anti-oxidative, anti-inflammatory properties of sulforaphane.

Reference: Nutrients; 2021, Vol. 13, No. 2, 352

Brain HealthNutrients protect against cognitive decline, improve brain functionVitamins C and E may lower chances for Pa...
09/21/2026

Brain Health

Nutrients protect against cognitive decline, improve brain function

Vitamins C and E may lower chances for Parkinson’s

In Parkinson’s disease (PD), brain-nerve function slowly deteriorates, with a wide range of eventual physical and cognitive symptoms including tremors and memory loss. While there is no apparent single cause, oxidative stress is a common factor.
In this study, doctors followed and gathered food questionnaires from 43,865 men and women, aged 18 to 94, who began the study without PD. Over 17.6 years of follow-up, overall, those with the highest levels of vitamins C or E were 32 percent less likely to have developed PD compared to those with the lowest levels of vitamins C or E.
Doctors concluded dietary vitamins C and E may reduce chances for PD.

Reference: Neurology; 2021, Vol. 96, No. 6

Heart Rate RecoveryOne of the best signs of good health is how quickly the heart returns to resting rate after exercise....
09/14/2026

Heart Rate Recovery

One of the best signs of good health is how quickly the heart returns to resting rate after exercise. In this study, doctors compared levels of omega-3 fatty acids and heart recovery rate in 13,912 healthy men and women, average age 50. A 2-percentage-point increase in omega-3s—where 8 percent is the ideal level—brought heart rate down 0.35 beats per minute (BPM) in men, and 0.69 BPM in women. Overall, men and women recovered an average 24 BPM after one minute, and 53 BPM after three minutes.
Doctors said, “omega-3s make the heart light on its feet, not sluggish in its response.”

Reference: Prostaglandins, Leukotrienes and Essential Fatty Acids; 2020 Dec; 163:102206

Magnesium in chronic kidney diseaseOne of the factors in kidney disease is poor circulation in calcified arteries, hampe...
09/07/2026

Magnesium in chronic
kidney disease
One of the factors in kidney disease is poor circulation in calcified arteries, hampering kidney filtering function. Playing off earlier studies that found magnesium slowed arterial calcification, doctors reviewed 22 studies covering over 200,000 chronic kidney disease patients.
Overall, those with higher—but not abnormally high—levels of magnesium were less likely to die from any cause compared to those with lower magnesium levels. Doctors found a direct link: for each 0.1 millimoles-per-liter of blood (mmol/L) increase in magnesium, chances for heart and circulatory adverse events, including dying, decreased by 15 percent. Doctors noted the optimum range for magnesium appears to be between 1.15 and 1.27 mmol/L.

Reference: Clinical Nutrition; 2020, 015

Tocotrienols improve kidney functionOne of the complications of types 1 and 2 diabetes is impaired kidney function. Evid...
08/31/2026

Tocotrienols improve
kidney function
One of the complications of types 1 and 2 diabetes is impaired kidney function. Evidence is mounting that the tocotrienol form of vitamin E has the unique ability to uniformly disperse throughout cells and pe*****te saturated fatty layers, making it a highly potent antioxidant.
In this study, 59 men and women, average age 67, with diabetic nephropathy—where kidneys can’t effectively filter waste and excess fluids—took a placebo or 200 mg of tocotrienols twice per day.
To assess kidney function, doctors measured creatinine, a waste product, levels of which were elevated in all participants. After six months, those taking tocotrienols saw a 3.2 percent decrease in creatinine levels compared to a 7.6 percent increase for placebo. Doctors also estimated how well the kidneys were filtering creatinine, and after six months found a 3.3 percent increase for tocotrienols and a 12.8 percent decrease for placebo. These benefits continued through the 12-month study period.
Discussing the findings, doctors said this is the first clinical trial to show tocotrienol-rich vitamin E supplements for 12 months slowed diabetic kidney disease, especially in its later stages.

Reference: Nutrients, 2021, Vol. 13, No. 1, 258

CoQ10 and beta-carotene low in oral cancerOxidative stress, inflammationThis is the first study to measure antioxidant v...
08/24/2026

CoQ10 and beta-carotene low in oral cancer

Oxidative stress, inflammation
This is the first study to measure antioxidant vitamin levels in those with oral cancer. Doctors in this study theorized cancer develops through oxidative stress and inflammatory processes linked to metabolic disorders.
Doctors measured CoQ10, beta-carotene, and metabolic factors in 194 people with oral cancer. More than half of participants had high blood pressure, blood sugar, and lipids; and abdominal obesity, regardless of the stage of their tumors.
Nearly all—94 percent—were deficient in CoQ10, and 46 percent were deficient in beta-carotene. Those with higher levels of CoQ10 or beta-carotene were less likely to have abdominal obesity, elevated lipids, or metabolic syndrome. Doctors also found, as the cancer advanced, levels of antioxidant enzyme activity decreased, and levels of inflammatory markers increased.
Discussing the findings, doctors said, “Since patients with oral cancer suffer from high oxidative stress and inflammation, supplementation with antioxidant vitamins such as ubiquinone (CoQ10) or beta-carotene could be beneficial.”

Reference: BMC Cancer; Article No. 310, 2020

Curcumin for PCOSPolycystic o***y syndrome (PCOS), is a condition where the ovaries produce an abnormal amount of androg...
08/17/2026

Curcumin for PCOS

Polycystic o***y syndrome (PCOS), is a condition where the ovaries produce an abnormal amount of androgens—male hormones. Insulin resistance and greater chances for developing diabetes often accompany PCOS. In this study, 67 women with PCOS took a placebo or 500 mg of curcumin three times per day.
After 12 weeks, fasting blood sugar levels declined an average of 4.11 milligrams per deciliter of blood (mg/dL) for curcumin compared to 0.35 mg/dL for placebo. Also, the male hormone precursor, dehydroepiandrosterone (DHEA), declined 26.53 micrograms per deciliter of blood (mcg/dL) for curcumin compared to 4.34 mcg/dL for placebo.
Estradiol, the female s*x hormone, had a slight increase in those taking curcumin compared to those in the placebo group. Doctors concluded curcumin safely reduced elevated blood sugar and male hormone levels in women with PCOS.

Reference: Phytomedicine, Vol. 80, January 2021, 153395

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