Pennyrile Precision Rx Consulting

Pennyrile Precision Rx Consulting Helping people understand how their DNA impacts how medications work for them.

I'm excited to make a new health solution available to members of my community! Precision Medicine can offer huge benefi...
04/23/2023

I'm excited to make a new health solution available to members of my community! Precision Medicine can offer huge benefits by helping guide medication usage.

By looking at your DNA, here are some things we can learn:
-Which medications are good for you to try
-Which medications you should avoid
-Which medications you are likely to have severe side effects or an adverse reaction from
-The best starting dose of certain medications
-Which medications are likely to not be effective for you

In addition to looking at your DNA to discover how your body will react to medication, I can also review your current medication list. This can help find drug combinations that are causing unwanted side effects, drug combinations that can negatively interact with your DNA, and additional medications you might benefit from based off your current health conditions. After this, I will create a personalized set of recommendations that we can send to your physician to make sure you medication regimen is as optimized as possible!

I'm currently looking for new patients to help! I would love to be able to reach out to you regarding this service.

You should fill out this form if you:
-have tried and failed multiple medications
-have had significant side effects from medications
-want to be proactive in learning which medications will work best for you
-want to learn how one test can impact medication prescribing for the rest of your life
-have a friend of family member who might benefit and you want to learn more
-are just interested in what I'm creating!

https://www.pennyrilerx.com/contact-request

04/06/2023
Part 4:Working with a PGx-based pharmacist therefore can provide several benefits beyond those already mentioned. One su...
03/22/2023

Part 4:
Working with a PGx-based pharmacist therefore can provide several benefits beyond those already mentioned. One such benefit is improved medication adherence. By providing patients with personalized medication plans based on their unique genetic makeup, PGx-based pharmacists can help patients understand the importance of taking their medications as prescribed, increasing the likelihood of medication adherence and improving patient outcomes. Another benefit is improved safety. Pharmacogenomic testing can help identify potential drug interactions and adverse drug reactions, allowing healthcare providers to make more informed decisions about medication choices and dosages, ultimately leading to safer patient care. PGx-based pharmacists can also provide education and support for patients, helping them to better understand their genetic test results and how they can use this information to make informed decisions about their healthcare. This personalized approach can lead to increased patient engagement and satisfaction.

In conclusion, working with a PGx-based pharmacist can provide several benefits for patients and healthcare providers, including improved medication adherence, improved safety, and personalized education and support. With access to the latest pharmacogenomic testing, as well as personalized medication plans, patients can receive more individualized care, ultimately leading to better patient outcomes. Healthcare providers can also benefit from the expertise and guidance of a PGx-based pharmacist, helping them to make more informed decisions about medication choices and dosages. Overall, working with a PGx-based pharmacist can provide a comprehensive approach to patient care that addresses both medication and nutritional needs, leading to improved patient outcomes and satisfaction.

Part 3:When it comes to pharmacogenomic testing, working with a PGx-based pharmacist offers a significant advantage over...
03/21/2023

Part 3:
When it comes to pharmacogenomic testing, working with a PGx-based pharmacist offers a significant advantage over relying solely on lab results. One of the critical areas where PGx-based pharmacists excel is in checking for the phenoconversion phenomenon, also known as drug-drug-gene interaction. Phenoconversion can occur when one drug affects the expression or activity of a specific gene, which can then affect the response to a second drug. This can lead to significant medication issues, including adverse drug reactions, increased risk of toxicity, or decreased drug efficacy. Unfortunately, labs do not typically check for this phenomenon, making it essential to work with a PGx-based pharmacist who has expertise in identifying potential drug-drug-gene interactions. By working with a PGx-based pharmacist, healthcare providers can identify potential drug-gene interactions and adjust the patient's medication regimen accordingly. This can help avoid adverse reactions, reduce the risk of toxicity, and improve the effectiveness of the prescribed medication. In addition, the PGx-based pharmacist can provide guidance and recommendations to healthcare providers on alternative medication options or dosages to optimize treatment. Working with a PGx-based pharmacist can therefore help in identifying potential drug-drug-gene interactions that labs may not typically check for, leading to better patient outcomes. Their expertise in pharmacogenomics and ability to identify potential medication issues can help healthcare providers make informed decisions about drug therapy, leading to more personalized and effective treatment for patients.

Part 2:Collaborating with a PGx-based pharmacist offers a seamless and efficient process to incorporate pharmacogenomic ...
03/20/2023

Part 2:
Collaborating with a PGx-based pharmacist offers a seamless and efficient process to incorporate pharmacogenomic testing into patient care. When working with a PGx-based pharmacist, they will take care of the administrative process, including ordering the labs, meeting with the patient, and billing the patient, leaving no administrative lift on the healthcare provider's end. Once the PGx results are available, the PGx-based pharmacist will create a Medication Action Plan (MAP), highlighting recommended medication changes based on the patient's genetic makeup. The healthcare provider can then review and discuss the recommendations with the PGx-based pharmacist, either via phone, email, or Zoom, allowing for seamless integration of personalized medicine into the patient's treatment plan. Working with a PGx-based pharmacist can help healthcare providers make informed decisions about medication based on a patient's genetic makeup. The process is streamlined and efficient, with the PGx-based pharmacist taking care of the administrative tasks, allowing the healthcare provider to focus on patient care. The PGx-based pharmacist's expertise in pharmacogenomics can help identify potential drug interactions or side effects that may be specific to a patient's genetic makeup, leading to better outcomes for patients.

Part 1:At a time when personalized medicine is becoming increasingly important, working with a PGx-based pharmacist can ...
03/19/2023

Part 1:
At a time when personalized medicine is becoming increasingly important, working with a PGx-based pharmacist can offer numerous benefits. A PGx-certified pharmacist has undergone specialized training in pharmacogenomics, which is the study of how a patient's genetic makeup can affect their response to medication. With their in-depth understanding of CPIC and PharmGKB guidelines, PGx-based pharmacists can help healthcare providers make more informed decisions about drug therapy based on individual patients' genetic profiles. One of the main reasons to work with a PGx-based pharmacist is that the FDA provides limited information on the effects of genetics on drug response, and the information provided may not be sufficient to make informed decisions. Therefore, a PGx-based pharmacist's knowledge can be valuable when working with patients whose genetics may influence their medication response. Additionally, they can help identify potential drug interactions or side effects that may be specific to a patient's genetic makeup and recommend alternative medications or dosages to optimize treatment. Working with a PGx-based pharmacist provides a unique opportunity to personalize drug therapy based on an individual's genetic makeup. Their expertise in pharmacogenomics and knowledge of CPIC and PharmGKB guidelines can help healthcare providers make more informed decisions about medication, leading to better outcomes for patients.

03/18/2023

What is pharmacogenomics?

Pharmacogenomics (sometimes called pharmacogenetics) is a field of research that studies how a person’s genes affect how he or she responds to medications. Its long-term goal is to help doctors select the drugs and doses best suited for each person. It is part of the field of precision medicine, which aims to treat each patient individually.

What role do genes play in how medicines work?

Just as our genes determine our hair and eye color, they partly affect how our bodies respond to medicine. Genes are instructions, written in DNA, for building protein molecules. Different people can have different versions of the same gene. Each version has a slightly different DNA sequence. Some of these variants are common, and some are rare. And some affect health, such as those gene variants linked to certain diseases. Scientists know that certain proteins affect how drugs work. Pharmacogenomics looks at variations in genes for these proteins. Such proteins include liver enzymes that chemically change drugs. Sometimes chemical changes can make the drugs more—or less—active in the body. Even small differences in the genes for these liver enzymes can have a big impact on a drug’s safety or effectiveness.

https://nigms.nih.gov/education/fact-sheets/Pages/pharmacogenomics.aspx

What is precision medicine?

According to the Precision Medicine Initiative, precision medicine is "an emerging approach for disease treatment and prevention that takes into account individual variability in genes, environment, and lifestyle for each person." This approach will allow doctors and researchers to predict more accurately which treatment and prevention strategies for a particular disease will work in which groups of people. It is in contrast to a one-size-fits-all approach, in which disease treatment and prevention strategies are developed for the average person, with less consideration for the differences between individuals.

Although the term "precision medicine" is relatively new, the concept has been a part of healthcare for many years. For example, a person who needs a blood transfusion is not given blood from a randomly selected donor; instead, the donor’s blood type is matched to the recipient to reduce the risk of complications. Although examples can be found in several areas of medicine, the role of precision medicine in day-to-day healthcare is relatively limited. Researchers hope that this approach will expand to many areas of health and healthcare in coming years.

https://medlineplus.gov/genetics/understanding/precisionmedicine/definition/

For all people, our DNA is 99.9% the same.(1) However, that 0.1% can make a big difference in how our bodies respond to ...
03/15/2023

For all people, our DNA is 99.9% the same.(1) However, that 0.1% can make a big difference in how our bodies respond to medications. Traditional prescribing practices use a once size fits all approach most of the time. What if you could have a more precise approach?

With precision medicine and pharmacogenomics, you get just that. I can help you understand your DNA and how it affects your body's response to different medications. I can help you and your physician know which medications are likely to not work for you or cause unwanted side effects. Then after we have reviewed your DNA, I can help you manage all your medications. Together, we can determine if you're having side effects from your drug combinations, explore if there are some medications we can discuss with your physician about discontinuing, and much more.

Take control of your health and learn about your DNA today!
www.pennyrilerx.com

(1) https://www.ncbi.nlm.nih.gov/books/NBK20363/

03/15/2023
03/15/2023

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Louisville, KY

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