Propolis Science

Propolis Science Contact information, map and directions, contact form, opening hours, services, ratings, photos, videos and announcements from Propolis Science, Alternative & holistic health service, Marietta, GA.

Propolis Science is your resource to discover and explore the amazing and diverse benefits, applications, and research that comes from the Beehive with a special focus on Propolis... as well as general information on these amazing bees.

06/20/2024
In the Face of Numerous Threats, Bees Are Producing Less Honey
06/19/2024

In the Face of Numerous Threats, Bees Are Producing Less Honey

Saving American honey production—and the beekeeping industry—will require a sea change in agricultural practices.

Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process...
06/19/2024

Main pathways of action of Brazilian red propolis on the modulation of neutrophils migration in the inflammatory process

Discovering Brazilian Red Propolis:

• Natural Anti-Inflammatory: Brazilian red propolis shows promise as a natural anti-inflammatory agent.
• Neutrophil Modulation: It modulates neutrophil migration, crucial in the body’s inflammatory response.
• Mechanism of Action: The propolis works by reducing leukocyte adhesion, cytokine and chemokine release, and blocking calcium influx in neutrophils.
• Potential Health Benefits: With its ability to control inflammation, Brazilian red propolis could be beneficial for various inflammatory conditions.
https://www.sciencedirect.com/science/article/pii/S0944711316301660

Antinociceptive and anti-inflammatory effects of Brazilian red propolis extract and formononetin in rodentsConclusions: ...
06/17/2024

Antinociceptive and anti-inflammatory effects of Brazilian red propolis extract and formononetin in rodents

Conclusions: The H**P [hydroalcoholic extract of red propolis] and formononetin presented significant anti-inflammatory activity. Moreover, the H**P presented antinociceptive action on inflammatory and neurogenic pain without motor side effects, possibly due to the action of other constituents present in the extract. These results, together, support the popular usage of this natural product.

Propolis has been used as a folk medicine for centuries around the world due to its wide spectrum of biological activities. The red propolis, a new Br…

Red Propolis as a Source of Antimicrobial Phytochemicals: Extraction Using High-Performance Alternative Solvents(FREE FU...
06/17/2024

Red Propolis as a Source of Antimicrobial Phytochemicals: Extraction Using High-Performance Alternative Solvents
(FREE FULL TEXT PDF)

Propolis is a resinous material rich in flavonoids and involved in several biological activities such as antimicrobial, fungicide, and antiparasitic function...

06/17/2024

"Bees will take their nutrients from anything which has sugar and moisture. Feeding them watermelon if conditions are tough is a good idea because it’s got plenty of fructose and moisture! The photo and information is from Heather Harvey, a park ranger with the National Park Service."

06/16/2024
A nice overview of Honey, historically and as a nutrient powerhouse and medicinal allyAncient Sweetener: Honey has been ...
06/15/2024

A nice overview of Honey, historically and as a nutrient powerhouse and medicinal ally

Ancient Sweetener: Honey has been revered since ancient times as a natural sweetener and a gift from nature, often called ‘the food of Gods’.
Nutritional Profile: Packed with carbohydrates, amino acids, minerals, and vitamins, honey offers immense nutritional benefits and is considered a multivitamin tonic.
Medicinal Uses: Its antimicrobial, antioxidant, and wound-healing properties make it a valuable component in traditional medicine for a variety of ailments.
Antibacterial Properties: The text outlines honey’s antibacterial activities, including its inhibitory effect on Helicobacter pylori and its role in combating antimicrobial resistance.
Adulteration Detection: Despite its high demand, honey adulteration is common, but modern techniques like NMR spectroscopy are improving the detection of such frauds.
(FREE FULL TEXT PDF)

Honey got its significance, both as medical and non-medical purposes. Honey is a complex matrix of several carbohydrates, amino acids, minerals and many more. Honey's carbohydrate components include a variety of mono- and disaccharide forms such as fructose, glucose, sucrose and other reducing sugar...

Anticancer Activity of Propolis and Its CompoundsPropolis is a natural material that honeybees produce from various bota...
06/12/2024

Anticancer Activity of Propolis and Its Compounds

Propolis is a natural material that honeybees produce from various botanical sources. It has been known for its therapeutic activity, including antibacterial, antifungal, and anti-inflammatory effects.

Recent research has shown that propolis is a rich source of biologically active compounds, which affect numerous signaling pathways regulating crucial cellular processes. These compounds can inhibit proliferation, angiogenesis, and metastasis of cancer cells and stimulate apoptosis. Moreover, propolis may influence the tumor microenvironment and multidrug resistance of cancers.

This suggests that propolis and its compounds have potential anticancer activity. They could be beneficial in reducing the side effects of chemotherapy and radiotherapy.

Propolis is a natural material that honey bees (Apis mellifera) produce from various botanical sources. The therapeutic activity of propolis, including antibacterial, antifungal, and anti-inflammatory effects, have been known since antiquity. ...

Unveiling the Phenolic Compounds of Chestnut Honey-Based Propolis and in Silico Phytoestrogen ActivityAn estrogen defici...
06/12/2024

Unveiling the Phenolic Compounds of Chestnut Honey-Based Propolis and in Silico Phytoestrogen Activity

An estrogen deficiency at menopause induces climacteric symptoms in humans including hot flashes, diaphoresis, sleep disturbances and progressive bone loss. A phytoestrogen can be defined as a plant-derived xenoestrogen molecule with estrogenic activity and not associated with the endocrine system. The present study aims to investigate the chemical constituents and their potency as a phytoestrogen of chestnut-honey based propolis from Çarşamba district (Samsun, Turkey) by in silico molecular docking simulation.

An estrogen deficiency at menopause induces climacteric symptoms in humans including hot flashes, diaphoresis, sleep disturbances and progressive bone loss. A phytoestrogen can be defined as a plant-derived xenoestrogen molecule with estrogenic activity and not...

06/12/2024

BRAZILIAN ORGANIC PROPOLIS FOR PREVENTION AND TREATMENT OF RADIATION-RELATED ORAL ACUTE TOXICITIES: A CLINICAL TRIAL.

Topic use of BOP reduced TNF-α and IL-1β levels, oral candidiasis episodes, and seems to be a useful alternative option for prevention and treatment of the main acute oral toxicities of RT.
https://www.sciencedirect.com/science/article/abs/pii/S2212440323013834

The purpose of this trial was to investigate the use of BOP as a preventive and/or complementary therapeutic option for radiotherapy-induced oral mucositis, dysphagia, dysgeusia, pain, and oral candidiasis. The study also assessed proinflammatory cytokines to investigate their anti-inflammatory role¹².

The trial included 60 patients who were randomized to receive either an aqueous suspension of BOP or a placebo throughout their radiotherapy treatment. All patients also underwent low-level laser therapy as routine oral care.

The results showed that patients in the propolis group had a lower mean score of oral mucositis, dysphagia, dysgeusia, and most patients reported moderate pain. Fewer patients developed oral candidiasis in the propolis group, and the number of episodes was lower among patients that used BOP. In addition, the BOP group presented significantly lower levels of IL-1β since the beginning of treatment when compared with placebo patients, and a lower level of TNF-α at the end of treatment.

This suggests that BOP could potentially be a beneficial supplement for patients undergoing radiotherapy for head and neck cancer. However, more research is needed to confirm these findings and to further explore the potential benefits and risks of BOP. It's always recommended to consult with healthcare professionals before starting any new treatment or supplement.

Send a message to learn more

Neonicotinoid Pesticides Keep Killing Pollinators. Here’s How We Can Help.Several states now restrict the use of these w...
06/12/2024

Neonicotinoid Pesticides Keep Killing Pollinators. Here’s How We Can Help.
Several states now restrict the use of these widespread insecticides in some way to help protect native bees and honeybees, the pollinators critical for our food supply. Every person with a yard can slow the decline, too.

Several states now restrict the use of these widespread insecticides to help protect native bees and honeybees, the pollinators critical for our food supply. Every person with a yard can slow the decline, too.

Flowers may electrically detect bees buzzing nearbyPlants could use those signals to time their nectar production
06/12/2024

Flowers may electrically detect bees buzzing nearby
Plants could use those signals to time their nectar production

The discovery may reveal how plants time nectar production and share information with neighboring blooms.

Study confirms bees are more sensitive to pesticides due to climate change
06/12/2024

Study confirms bees are more sensitive to pesticides due to climate change

A study led by CREAF and the UAB, and published in Global Change Biology, discovered that warmer winters worsen the impact of pesticides on bees and reduce their life expectancy by 70%, causing severely negative effects on the population and a sharp decline in the number of pollinators.

How can a backyard garden help butterflies and bees?
06/12/2024

How can a backyard garden help butterflies and bees?

Native plants are valued by gardeners because native wildlife have relied on those plants for centuries. But which plants are the most beneficial for butterflies, bees and other insects, and how can you tell if a plant is truly native?

Cytotoxic, proapoptotic and antioxidative potential of flavonoids isolated from propolis against colon (HCT-116) and bre...
06/04/2024

Cytotoxic, proapoptotic and antioxidative potential of flavonoids isolated from propolis against colon (HCT-116) and breast (MDA-MB-231) cancer cell lines

Researchers investigated the anti-cancer potential of flavonoids, natural compounds found in propolis, against colon and breast cancer cells. They isolated and tested eleven flavonoids on human colon (HCT-116) and breast (MDA-MB-231) cancer cell lines. Six flavonoids showed cytotoxicity, meaning they inhibited the growth of cancer cells. Luteolin was particularly effective, with the strongest inhibitory effect on both colon and breast cancer cells.

The study also examined how these flavonoids induced apoptosis, or programmed cell death, in cancer cells. Again, luteolin displayed the highest apoptotic potential. Interestingly, some flavonoids exhibited pro-oxidative effects at early stages (24 hours) but transitioned to antioxidant effects later (72 hours). Overall, the findings suggest these flavonoids have promising potential for developing new cancer drugs due to their cytotoxic, pro-apoptotic, and antioxidant properties.

This paper discusses the potential of propolis, a resinous substance produced by honeybees, to treat various gastrointes...
06/04/2024

This paper discusses the potential of propolis, a resinous substance produced by honeybees, to treat various gastrointestinal disorders. Researchers have been exploring propolis as a source for new treatments due to the prevalence of gastrointestinal issues. The review examines published research on propolis and its components to determine its effectiveness in treating these conditions.

The paper highlights propolis’s potential to be effective against conditions like gastritis, ulcers, colitis, and even gastrointestinal cancers. The anti-inflammatory and antioxidant properties of propolis are suggested as the reasons behind its effectiveness. Overall, the review suggests propolis shows promise as a treatment for gastrointestinal disorders.
(FREE FULL TEXT PDF)

There are a number of disorders that affect the gastrointestinal tract. Such disorders have become a global emerging disease with a high incidence and prevalence rates worldwide. Inflammatory and ulcerative processes of the stomach or intestines, such as gastritis, ulcers, colitis, and mucositis, af...

Experimental Evidence for Therapeutic Potentials of PropolisPropolis Origins: Propolis, also known as 'bee glue,' is pro...
06/04/2024

Experimental Evidence for Therapeutic Potentials of Propolis

Propolis Origins: Propolis, also known as 'bee glue,' is produced by honeybees from plant materials. It has been used in traditional healthcare since ancient times due to its therapeutic properties.

This paper discusses the bioactive components of propolis, such as Artepillin C (ARC) and caffeic acid phenethyl ester (CAPE), which have been found to possess anticancer, antistress, and hypoxia-modulating activities.

https://www.mdpi.com/2072-6643/13/8/2528

World Bee Day 2024: Bee engaged with youthBees and other pollinators, such as butterflies, bats, and hummingbirds, are i...
05/20/2024

World Bee Day 2024: Bee engaged with youth

Bees and other pollinators, such as butterflies, bats, and hummingbirds, are increasingly under threat due to human activities. Pollination is vital for the survival of ecosystems, with nearly 90% of wild flowering plant species and over 75% of food crops relying on animal pollination.

World Bee Day 2024 focuses on the theme “Bee engaged with Youth,” emphasizing the involvement of young people in pollinator conservation.

Another threat to bees: Climate change-fueled rising temperaturesWarming temperatures could be responsible for a worldwi...
05/15/2024

Another threat to bees: Climate change-fueled rising temperatures

Warming temperatures could be responsible for a worldwide bumblebee decline, a new analysis finds — and the damage may rise as temperatures soar because of climate change.

A study looked at heat stress in bumblebees and how that might affect their nests.

Photo by Anna Laura monticolo
05/15/2024

Photo by Anna Laura monticolo

Therapeutic Potential of Withaferin-A and Propolis Combinational Drug Therapy for Breast Cancer: An In Vivo Interpretati...
05/15/2024

Therapeutic Potential of Withaferin-A and Propolis Combinational Drug Therapy for Breast Cancer: An In Vivo Interpretation for Validating the Antiproliferative Efficacy and Ameliorative Potential in Benzo[a]pyrene-Induced Breast Metastasis

Withaferin-A and propolis drug combination treatment significantly decreased nucleic acid synthesis, indicating that combination chemotherapy has increased breast tumoricidal efficiency. The pharmacological combination therapy exhibited the capacity to control glycoproteins associated with tumor growth (hexose, hexosamine, and sialic acid), with a considerable decrease in their levels detected. Histopathological analysis of the mammary glands demonstrated a decrease in hyperplasia and cell proliferation, indicating that the treatment has the ability to reverse architectural and morphological abnormalities associated with breast cancer. This study found that natural drug compounds in combination have shown regenerative and regulating effects when given to rats carrying the breast cancer gene.
(FREE FULL TEXT PDF)
https://www.hindawi.com/journals/jchem/2024/8491275/

In vivo anti-inflammatory activity of BACCHARIN from BRAZILIAN green PROPOLISThere was no evidence of kidney and liver t...
05/15/2024

In vivo anti-inflammatory activity of BACCHARIN from BRAZILIAN green PROPOLIS

There was no evidence of kidney and liver toxicity and neurodepressive potential at the doses tested. Thus, baccharin has a promising anti-inflammatory effect possibly associated with antiedematogenic activity by inhibiting mediators such as prostaglandins, inhibiting the migration of polymorphonuclear cells, and modulating NF-kB expression.
https://www.sciencedirect.com/science/article/abs/pii/S0367326X24001588

Brazilian green propolis prevent Alzheimer’s disease-like cognitive impairment induced by amyloid beta in miceConclusion...
11/28/2023

Brazilian green propolis prevent Alzheimer’s disease-like cognitive impairment induced by amyloid beta in mice

Conclusions: The results suggest that the prophylactic administration of Brazilian green propolis has a preventive effect against Alzheimer’s disease by suppressing excessive inflammation and immune response in glial cells. To our knowledge, this study is the first to demonstrate that Brazilian green propolis may inhibit the hyperactivation of microglia and astrocytes as a mechanism of action to prevent Alzheimer’s disease. Thus, it is a promising ingredient for preventing Alzheimer’s disease-type dementia.
(FREE FULL TEXT PDF)

Background The increasing incidence of cognitive impairment has become a health problem in the aging society. Owing to its antioxidant and anti-inflammatory properties, Brazilian green propolis—derived from Baccharis dracunculifolia—is anticipated to possess anticognitive properties. However, th...

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