Rx Formulations

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Rx Formulations RxFormulations is a Mesa-based compounding pharmacy providing clean, custom prescriptions and collaborative pharmacy services.

Serving Arizona with personalized preparation and provider support.

Today is World Osteoporosis Day.One in three women over 50 will experience an osteoporosis-related fracture in their lif...
10/20/2026

Today is World Osteoporosis Day.

One in three women over 50 will experience an osteoporosis-related fracture in their lifetime. Most of the bone protection conversation happens after menopause. Most of the bone loss begins in perimenopause.

Estrogen is the primary regulator of bone turnover in women. It maintains equilibrium between bone resorption and formation by modulating osteoblast survival and osteoclast activity. When estrogen declines, resorption accelerates. A 2025 scoping review in Frontiers in Reproductive Health found that menopausal hormone therapy reduces bone resorption and, in combination with resistance exercise, supports bone mineral density through complementary and additive mechanisms (Alferaih et al., Front Reprod Health, 2025 — https://doi.org/10.3389/frph.2025.1542746).

Timing matters. The protective effect of hormone therapy on bone density is most pronounced when initiated closer to the onset of menopause, not years later. Lower-dose transdermal formulations can conserve bone while carrying a more favorable cardiovascular and VTE risk profile. Dose adequacy, however, is individual and requires lab monitoring rather than default assumptions (Stevenson et al., 2023 — https://doi.org/10.1177/20533691221139902).

At RxFormulations, we compound hormone therapy to the individual dose a prescriber determines is adequate for that patient. This is where compounding adds clinical value that commercial fixed-dose products cannot.

Comment 𝗖𝗢𝗡𝗦𝗨𝗟𝗧 to connect.

📍 RxFormulations | Mesa, AZ | 480-854-3100

10/19/2026

Two of the most commonly prescribed supplements at our compounding pharmacy are also two of the most commonly misused in terms of timing and form. Vitamin D and iron are not complicated, but the details matter.

Vitamin D is fat-soluble, meaning it requires dietary fat for absorption in the small intestine. Taking it on an empty stomach or with a low-fat meal limits how much reaches circulation. Taking it with vitamin K2 (MK-7 specifically) adds the downstream benefit of directing calcium to bone rather than arterial tissue. D3 is the preferred form over D2 for conversion efficiency.

Iron absorption is significantly reduced by calcium, dairy, coffee, tea, high-fiber foods, and antacids. These interactions are well-established in the pharmacological literature on iron absorption and are a routine part of medication counseling at RxFormulations. Iron bisglycinate is consistently better tolerated than ferrous sulfate and is the form our pharmacists recommend when patients experience GI side effects that cause them to stop their course. The supplement you discontinue produces no result regardless of its chemistry.

Vitamin D and iron do not compete for absorption and can be taken together if necessary. The issue is not combining them. It is taking either in a form or at a time that limits how much your body uses.

Comment 𝗦𝗨𝗣𝗣𝗟𝗘𝗠𝗘𝗡𝗧 below to review your supplement timing and form.

📍 RxFormulations | Mesa, AZ | 480-854-3100

𝘎𝘦𝘯𝘦𝘳𝘢𝘭 𝘱𝘩𝘢𝘳𝘮𝘢𝘤𝘺 𝘢𝘯𝘥 𝘤𝘭𝘪𝘯𝘪𝘤𝘢𝘭 𝘯𝘶𝘵𝘳𝘪𝘵𝘪𝘰𝘯 𝘬𝘯𝘰𝘸𝘭𝘦𝘥𝘨𝘦. 𝘐𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭 𝘯𝘦𝘦𝘥𝘴 𝘴𝘩𝘰𝘶𝘭𝘥 𝘣𝘦 𝘥𝘪𝘴𝘤𝘶𝘴𝘴𝘦𝘥 𝘸𝘪𝘵𝘩 𝘢 𝘲𝘶𝘢𝘭𝘪𝘧𝘪𝘦𝘥 𝘱𝘩𝘢𝘳𝘮𝘢𝘤𝘪𝘴𝘵 𝘰𝘳 𝘩𝘦𝘢𝘭𝘵𝘩𝘤𝘢𝘳𝘦 𝘱𝘳𝘰𝘷𝘪𝘥𝘦𝘳.

Fall supplement planning from a compounding pharmacy is not the same conversation as what a health influencer recommends...
10/17/2026

Fall supplement planning from a compounding pharmacy is not the same conversation as what a health influencer recommends. It starts with what your labs show, what you are already taking, and what you actually need.

Vitamin D is the first priority for most patients heading into fall. Levels that were adequate in summer decline as outdoor time decreases, and the consequences include impaired immune function, mood disruption, and sleep fragmentation. A 2024 review in the American Journal of Lifestyle Medicine confirmed vitamin D among the micronutrients with physiological mechanisms supporting sleep quality (Esquivel and Ghosn, AJLM, 2024 — https://doi.org/10.1177/15598276241227915).

Zinc is the second. A 2024 systematic review in Health Science Reports found zinc supplementation may support sleep quality through melatonin pathway influence, alongside its well-established role in immune cell function (Jazinaki et al., HSR, 2024 — https://doi.org/10.1002/hsr2.70019). Form matters: bisglycinate and picolinate absorb more reliably than oxide.

Magnesium glycinate for sleep and nervous system recovery, omega-3 for inflammation management, and melatonin (compounded at appropriate low doses where needed) complete the fall protocol we discuss most often.

Bring your current supplement list for a free review. Comment 𝗦𝗨𝗣𝗣𝗟𝗘𝗠𝗘𝗡𝗧 below.

📍 RxFormulations | Mesa, AZ | 480-854-3100

10/16/2026

At RxFormulations, the question patients ask most often about LIVGAC is why it is administered by injection rather than taken as a capsule. The answer is absorption math.

Oral L-carnitine bioavailability from dietary sources is approximately 14 to 18%. Supplemental oral carnitine is absorbed more efficiently but is still subject to gut transporter saturation and first-pass effects, limiting how much reaches systemic circulation. Oral L-arginine is substantially metabolized by gut mucosa and hepatic tissue before entering systemic circulation, which is why the performance research on oral arginine shows inconsistent results at standard doses. Oral L-glutamine is partially consumed by enterocytes, the gut lining cells that use glutamine as their primary fuel, before the remainder reaches the bloodstream.

Injectable delivery bypasses all of these absorption barriers. The dose delivered is the dose that reaches circulation. This is why the same three amino acids that underperform as oral supplements can deliver a different response when administered parenterally.

Comment 𝗖𝗢𝗡𝗦𝗨𝗟𝗧 to learn more about LIVGAC.

📍 RxFormulations | Mesa, AZ | 480-854-3100

𝘎𝘦𝘯𝘦𝘳𝘢𝘭 𝘩𝘦𝘢𝘭𝘵𝘩 𝘢𝘯𝘥 𝘸𝘦𝘭𝘭𝘯𝘦𝘴𝘴 𝘴𝘶𝘱𝘱𝘰𝘳𝘵. 𝘕𝘰𝘵 𝘪𝘯𝘵𝘦𝘯𝘥𝘦𝘥 𝘵𝘰 𝘥𝘪𝘢𝘨𝘯𝘰𝘴𝘦, 𝘵𝘳𝘦𝘢𝘵, 𝘤𝘶𝘳𝘦, 𝘰𝘳 𝘱𝘳𝘦𝘷𝘦𝘯𝘵 𝘢𝘯𝘺 𝘥𝘪𝘴𝘦𝘢𝘴𝘦. 𝘐𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭 𝘳𝘦𝘴𝘶𝘭𝘵𝘴 𝘷𝘢𝘳𝘺.

Personalized medicine is the term healthcare is converging on. The idea that treatment should be calibrated to the indiv...
10/15/2026

Personalized medicine is the term healthcare is converging on. The idea that treatment should be calibrated to the individual, not the average. That dose, form, route, and timing should be determined by biology, not by what was most cost-effective to manufacture at scale.

At RxFormulations, this is not a future-state ambition. It is how we have dispensed since 2002. Every compounded prescription we fill is individualized by definition: the dose, the form, the delivery method, and the formulation are all determined by the prescriber and the patient, not the commercial inventory.

The blog we just published explores what personalized medicine means for the East Valley, where it intersects with compounding pharmacy, and why RxFormulations is positioned at that intersection by design.

Link in bio, or comment 𝗕𝗟𝗢𝗚𝟭𝟰 and we will send it directly.

📍 RxFormulations | Mesa, AZ | 480-854-3100

October is World Menopause Month.Women navigating hormonal health deserve providers who understand the full clinical pic...
10/13/2026

October is World Menopause Month.

Women navigating hormonal health deserve providers who understand the full clinical picture: the hormones, the timing, the individual biology, and the gap between what commercial pharmacies carry and what patients actually need.

Dr. Terry Huff brings over 30 years of comprehensive OB-GYN care to the East Valley, currently serving as chairman of the OB-GYN department at Banner Gateway Medical Center.

Dr. Linda Sodoma (lindasodomadoplc.com) leads a practice focused on hormone imbalance, menopause, and personalized gynecological care.

at Livengood Health delivers integrative primary care that integrates conventional and natural medicine with a focus on hormone regulation and root-cause wellness.

If you are a provider in the East Valley looking to build a referral relationship with a PCAB-accredited compounding pharmacy, comment 𝗣𝗔𝗥𝗧𝗡𝗘𝗥 below.

📍 RxFormulations | Mesa, AZ | 480-854-3100

10/12/2026

At RxFormulations, LIVGAC's patient base skews toward women, and that is not a coincidence.

Women have lower baseline carnitine stores than men, in part because carnitine is stored predominantly in skeletal muscle and women have less muscle mass by proportion. This makes the supply-demand gap for fatty acid transport into mitochondria more pronounced during exercise. Women also have lower arginine synthesis capacity from citrulline due to sex-based differences in urea cycle enzyme activity, which directly affects nitric oxide production and vascular efficiency during physical effort.

A 2025 narrative review in the Journal of the International Society of Sports Nutrition found that women have lower baseline creatine stores than men and that hormonal fluctuations through perimenopause alter amino acid metabolism in clinically meaningful ways, with implications for energy, muscle, and recovery (Smith-Ryan et al., JISSN, 2025 — https://doi.org/10.1080/15502783.2025.2502094). The same principle applies across the LIVGAC stack.

Glutamine demand also rises with immune challenge, physical stress, and hormonal fluctuation. Perimenopausal women face all three simultaneously. LIVGAC, delivered by injection to bypass first-pass absorption, is the most direct way to address that combined gap.

Comment 𝗖𝗢𝗡𝗦𝗨𝗟𝗧 to learn more about LIVGAC.

📍 RxFormulations | Mesa, AZ | 480-854-3100

𝘎𝘦𝘯𝘦𝘳𝘢𝘭 𝘩𝘦𝘢𝘭𝘵𝘩 𝘢𝘯𝘥 𝘸𝘦𝘭𝘭𝘯𝘦𝘴𝘴 𝘴𝘶𝘱𝘱𝘰𝘳𝘵. 𝘕𝘰𝘵 𝘪𝘯𝘵𝘦𝘯𝘥𝘦𝘥 𝘵𝘰 𝘥𝘪𝘢𝘨𝘯𝘰𝘴𝘦, 𝘵𝘳𝘦𝘢𝘵, 𝘤𝘶𝘳𝘦, 𝘰𝘳 𝘱𝘳𝘦𝘷𝘦𝘯𝘵 𝘢𝘯𝘺 𝘥𝘪𝘴𝘦𝘢𝘴𝘦. 𝘐𝘯𝘥𝘪𝘷𝘪𝘥𝘶𝘢𝘭 𝘳𝘦𝘴𝘶𝘭𝘵𝘴 𝘷𝘢𝘳𝘺.

Today is World Mental Health Day. 🍃The data on perimenopause and psychiatric risk is more striking than most people real...
10/10/2026

Today is World Mental Health Day. 🍃

The data on perimenopause and psychiatric risk is more striking than most people realize, and it rarely makes it into standard mental health conversations.

A landmark 2024 study in Nature Mental Health, analyzing data from over 128,000 women in the UK Biobank, found that the four years surrounding the final menstrual period represent a high-risk window for first-onset psychiatric diagnoses. Major depressive disorder risk rose by 30%, and first-onset bipolar manic episodes by 112%, in women with no prior psychiatric history (Di Florio et al., Nature Mental Health, 2024). These were not recurrences. They were first-time events.

A 2025 narrative review in the International Journal of Gynecology and Obstetrics found that transdermal 17-beta-estradiol may have antidepressant effects in perimenopausal women, while synthetic progestins may attenuate those benefits. Micronized progesterone is associated with a more favorable mood and cognitive profile (Yende et al., IJGO, 2025 — https://doi.org/10.1002/ijgo.70728).

At RxFormulations, we compound transdermal estradiol and micronized progesterone to individual lab-based specifications. This is the form of hormone therapy the evidence supports for mood-relevant applications.

Comment 𝗖𝗢𝗡𝗦𝗨𝗟𝗧 to connect with us.

📍 RxFormulations | Mesa, AZ | 480-854-3100

10/08/2026

Hormone therapy patients ask about estrogen delivery format more than almost any other clinical question, and the answer is not interchangeable. Gel, patch, and vaginal estrogen are not just different ways to take the same thing. They are different tools for different clinical problems.

Patches deliver steady-state transdermal estradiol, bypass hepatic first-pass metabolism, and are preferred for women with cardiovascular or thrombotic risk. Gels offer similar liver-bypass advantages with more dose flexibility but more absorption variability. Both require lab monitoring: a 2024 real-world study in Menopause documented up to 10-fold variability in serum estradiol between women using the same patch or gel dose, confirming that dose-based assumptions are insufficient (Yland et al., Menopause, 2024 — https://pmc.ncbi.nlm.nih.gov/articles/PMC12147738/).

Vaginal estrogen is local, not systemic. It targets genitourinary tissue and does not reliably treat vasomotor symptoms at standard low doses. A 2025 narrative review confirmed it as first-line for genitourinary syndrome of menopause, with minimal systemic absorption (Menopause journal, 2025 — https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12652300/).

Commercial products exist in fixed doses and standard forms. When a prescriber needs something different, they call RxFormulations.

Comment 𝗖𝗢𝗡𝗦𝗨𝗟𝗧 to connect.

📍 RxFormulations | Mesa, AZ | 480-854-3100

October is Breast Cancer Awareness Month.One of the most undertreated consequences of breast cancer treatment is genitou...
10/05/2026

October is Breast Cancer Awareness Month.

One of the most undertreated consequences of breast cancer treatment is genitourinary syndrome of menopause, and it affects up to 84% of women who go through treatment-induced menopause. Vaginal dryness, pain, urinary changes, and recurrent infections are not inevitable. They are treatable. And the safety data on vaginal estrogen has evolved significantly.

A 2023 study in JAMA Oncology found that vaginal estrogen use in breast cancer survivors was not associated with increased recurrence risk or breast cancer-specific mortality, shifting the clinical conversation about what survivorship care can include (Holmberg et al., 2023 — https://doi.org/10.1001/jamaoncology.2023.2609).

RxFormulations prepares vaginal estrogen formulations at custom concentrations and in allergen-free vehicles for survivorship patients whose needs cannot be met by commercial products. This requires a prescription and coordination with the treating oncologist or OB-GYN.

Comment 𝗖𝗢𝗡𝗦𝗨𝗟𝗧 to learn more about our survivorship compounding services.

📍 RxFormulations | Mesa, AZ | 480-854-3100

Address

5949 E University Drive
Mesa, AZ
85205

Opening Hours

Monday 8am - 5pm
Tuesday 8am - 5pm
Wednesday 8am - 5pm
Thursday 8am - 5pm
Friday 8am - 5pm

Telephone

+14808543100

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