Pure Life Longevity

08/17/2026

I LOVE this thing. 🤍

I’ve been playing with the Mira Hormone Monitor, and this is one of those tools that has genuinely made me curious.
Mira allows you to quantitatively track FSH, LH, E3G (an estrogen metabolite) and PdG (a progesterone metabolite) in urine — at home — so instead of seeing one isolated hormone value on one particular day, you can begin to see the pattern over time.

I have a family member using it, and I’m personally using it as well.
And because I’m me… I’m taking it a step further. 😊
I’m going to be running conventional laboratory testing alongside my Mira measurements so I can see how the trends compare — Mira urinary E3G vs. serum estradiol, PdG vs. progesterone, FSH, LH, timing, fluctuations, and overall patterns.

There is already some interesting science behind this.
One study looking at at-home urinary estrogen monitoring reported that:
“Matched daily samples confirmed good correlation of urine E3G and serum E2.”
Another study evaluating urinary and serum hormones concluded:
“Urine and serum hormones maintain a close relationship in women into their sixth decade of life.”
And research specifically using Mira has shown that quantitative at-home hormone monitoring can identify meaningful changes in reproductive hormone patterns.
What I find especially interesting is the ability to look at trends rather than relying solely on a single snapshot in time.
That said, Mira is measuring urinary hormones/metabolites, and those numbers should not be interpreted as interchangeable with conventional serum values. I still consider laboratory testing an important part of clinical assessment.
But as an additional tool?
I think this has the potential to be incredibly useful.
I’ll keep you posted as I collect more of my own data and compare what Mira is showing me with conventional labs. I’m especially interested in what this may teach us about hormone variability and individualized hormone therapy.
Stay tuned. I have a feeling I’m going to have a lot to say about this one. 😊
Interested in trying Mira yourself?
👉 https://mira-fertility.pxf.io/zzB9L7

08/17/2026

Remembering my recent training, I just had to repost this because it was just that memorable

✨ This weekend I had the privilege of spending time at REVANCE HQ in Nashville—and wow, what an amazing and inspiring company! Even more special was the chance to learn directly from Haley Wood.

Not going to lie… I was fangirling out 🤩 I’ve followed Haley for years, and finally getting to learn from her in person was beyond inspiring.

Forever grateful for opportunities like this to keep growing, learning, and bringing the very best back to my patients and practice. 💙✨

08/05/2026

Stress. Anxiety. An overdriven sympathetic nervous system.

Sound familiar? I've been using my Sensate for a couple weeks now and I'm genuinely impressed. It's a small device that uses gentle vibration and resonant tones through your sternum to activate your vagus nerve and shift your body into a calmer, more parasympathetic state. Ten minutes with it and I notice a real difference in how I feel, less wired, more grounded, better sleep that night.

Stress management is such an underrated piece of the longevity puzzle. We talk a lot about hormones, nutrition, and supplements, but if your nervous system stays stuck in fight-or-flight, none of that works as well as it should.

If you're curious about trying one for yourself, there's a special offer through the link below. And if you'd rather talk through how vagal tone and stress resilience fit into your own health picture, you can find me through the link in my bio.

https://getsensate.com/PURELIFELONGEVITY

08/05/2026

I'm back — and better than ever.
Welcome to Pure Life Longevity. Same passion for helping you feel your best, now with a sharper focus: hormone and metabolic optimization, immune and energy support.

Medicine that optimizes, not just manages.

Link in bio.

07/13/2026

Ever heard of C15:0?
It's a fatty acid our modern diets have quietly lost — and one of the more interesting molecules to come out of longevity science lately. It supports cell membrane stability, healthy metabolism, and a balanced inflammatory response, all in a single once-daily capsule.

The part I love: you can actually measure it. I broke down what the research shows, and how to test your levels, on the blog 👇
https://www.purelifelongevity.com/blog/the-fat-we-stopped-eating-and-why-it-might-matter-more-than-we-thought

You can also order fatty15 directly through the link on the blog post.

Integrative Health Consulting, Utilizing Functional Medicine to dig deep and identify root causes

07/13/2026

This was worth reposting…

I 💛 Bees. They are vital to our planet and these small, amazing creatures give back so much.
The uses that we can give to honey are very varied, from sweetener to medicinal remedy, —even beauty treatments.

07/07/2026

Something new is coming. 🌿

After more than two decades in clinical practice, I'm launching Pure Life Longevity — a telehealth practice built around hormone, metabolic, thyroid, and longevity care for women and men across Massachusetts and New Hampshire.

I'm Lorelee Scipione, PA-C, a Board-Certified Physician Associate and A4M Diplomate, and this page is where I'll be sharing what I'm learning and loving along the way: HRT research and breakthroughs, supplement science, longevity studies, and the everyday tools I actually use.

Consultations aren't open quite yet, but you can get a first look at the site and join the waitlist to be the first to know when I do. Stay tuned. 👇
purelifelongevity.com

11/17/2023

🌿 Unlocking the Power of Curcumin 🌟 Did you know that I 🧡 Curcumin? A whole lot! 🌈 Let me share some fascinating findings from a groundbreaking 18-month study conducted at UCLA! 🧠✨

👩‍🔬 In a double-blind, placebo-controlled trial involving 40 participants aged 51-84 with mild cognitive impairment, curcumin emerged as a potential game-changer. The study revealed that this natural wonder might not only prevent but also reverse cognitive decline.

📈 Gold standard assessments showcased noticeable improvements in memory and attention in adults. 🧠💡 But that's not all – brain scans before and after treatment demonstrated objective decreases in plaque and tangle accumulation in brain regions linked to mood and memory! 🌐✨

🌿 Curcumin's anti-amyloid and anti-inflammatory effects seem to shield the brain from neurodegeneration, making it a must-have supplement. 💊 Not just a potent anti-inflammatory, it's also a master antioxidant, elevating its status in the wellness realm.

💬 Intrigued? Let's dive deeper into this powerful ally for brain health! 🌐 Schedule an appointment at www.purelifewellness.me and let's chat about everything wellness. 🌟✨ 🌿💙

11/17/2023

09/19/2023

Welcome to my new space. 🧡 Openings in January. Reach out if you are interested in booking something. Please check out my website for services.
www.purelifewellness.me