Genes & Cancer

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Genes & Cancer Publishes original studies and reviews that are relevant to all aspects of cancer research, signal transduction, and developmental biology

Having served as the founding editor of Oncogene from 1987 to 2008 and establishing Oncogene as one of the leading cancer journals, Dr. E. Premkumar Reddy launched the journal entitled Genes & Cancer in 2010 which publishes original studies and reviews that are relevant to all aspects of cancer research, signal transduction, and developmental biology. Its Editorial Board consists of outstanding scientists who are well known for their contributions in the fields of oncogenes/oncoproteins, signal transduction, cancer therapy and other fields of biology and medicine. One of the important goals of the Editorial Office is to shape this journal into a high impact journal. All papers appear in PMC and PubMed. Based on our calculation, Genes & Cancer will soon become a very high impact journal. Genes & Cancer is a member of the Committee on Publication Ethics (COPE) and other international committees.

📕 Read the Genes & Cancer Publication Ethics and Publication Malpractice Statements:https://www.genesandcancer.com/ethic...
10/23/2026

📕 Read the Genes & Cancer Publication Ethics and Publication Malpractice Statements:
https://www.genesandcancer.com/ethics-statement/

Genes & Cancer is a peer-reviewed, open-access journal covering the genetic and molecular basis of cancer.

: "Using quantitative immunohistochemistry in patients at high risk for hepatocellular cancer"DOI ⬇️ https://doi.org/10...
10/23/2026

: "Using quantitative immunohistochemistry in patients at high risk for hepatocellular cancer"

DOI ⬇️
https://doi.org/10.18632/genesandcancer.220

Hepatocellular carcinoma (HCC) is the primary form of liver cancer and a major cause of cancer death worldwide. Early detection is key to effective treatment. Yet, early diagnosis is challenging, espe

🧬 Genes & Cancer covers the structure and function of oncogenes, tumor suppressor genes, and apoptotic genes, their role...
10/22/2026

🧬 Genes & Cancer covers the structure and function of oncogenes, tumor suppressor genes, and apoptotic genes, their roles in signal transduction, and how their expression and function change during tumor development.

🔗 https://www.genesandcancer.com/

Genes & Cancer is a peer-reviewed, open-access journal covering the genetic and molecular basis of cancer.

: "Expression of HOTAIR and MEG3 are negatively associated with H. pylori positive status in gastric cancer patients"DO...
10/22/2026

: "Expression of HOTAIR and MEG3 are negatively associated with H. pylori positive status in gastric cancer patients"

DOI ⬇️
https://doi.org/10.18632/genesandcancer.219

Background: Chronic infection with Helicobacter pylori is one of the main causes of gastric cancer (GC). Besides, lncRNAs play crucial roles in cancer pathobiology including GC. Here we aimed to inves

: "Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grad...
10/21/2026

: "Increased expression of BRD4 isoforms long (BRD4-L) and short (BRD4-S) promotes chemotherapy resistance in high-grade serous ovarian carcinoma"

DOI ⬇️
https://doi.org/10.18632/genesandcancer.233

Chemoresistance in ovarian carcinoma is a puzzling issue that urges understanding of strategies used by cancer cells to survive DNA damage and to escape cell death. Expanding efforts to understand mec

🧬 :Amir Hossein Alipour discusses a paper he co-authored, titled “Epstein-Barr virus nuclear antigen 1 upregulates De...
10/20/2026

🧬 :
Amir Hossein Alipour discusses a paper he co-authored, titled “Epstein-Barr virus nuclear antigen 1 upregulates Derlin1 and PSMD10 expression in HeLa cells.”

🎥 https://www.youtube.com/watch?v=3t-kpr-wank

Amir Hossein Alipour, from the Department of Microbiology and Immun...

: "A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case rep...
10/20/2026

: "A novel t (5; 17) (q35; q21) associated with t (8; 21) (q22; q22) in a patient with acute myeloid leukemia: case report and review of literature"

DOI ⬇️
https://doi.org/10.18632/genesandcancer.232

The t (8; 21) (q22; q22) with the resulting RUNX1- RUNX1T1 rearrangement is one of the most common cytogenetic abnormalities in acute myeloid leukemia (AML). It is associated with favorable prognosis.

: "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic tar...
10/19/2026

: "VCP/p97, a pleiotropic protein regulator of the DNA damage response and proteostasis, is a potential therapeutic target in KRAS-mutant pancreatic cancer"

DOI ⬇️
https://doi.org/10.18632/genesandcancer.231

We and others have recently shown that proteins involved in the DNA damage response (DDR) are critical for KRAS-mutant pancreatic ductal adenocarcinoma (PDAC) cell growth in vitro. However, the CRISPR

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