09/23/2026
What Are the Symptoms and Complications?
Sickle cell disease can cause:
🩸 Pain crises:
When sickle-shaped cells block blood flow, they can cause sudden and sometimes severe pain.
😴 Anemia:
Sickle cells break down earlier than healthy red blood cells, reducing the amount of oxygen delivered throughout the body. This can cause tiredness and weakness.
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🦠 Infections:
People with sickle cell disease, especially children, have an increased risk of serious infections.
🫁 Breathing problems:
Acute chest syndrome can cause chest pain, coughing, difficulty breathing, and fever. It requires immediate medical attention.
🧠 Stroke:
Blocked blood flow to the brain can cause a stroke.