Appelusa Functional Health & Wellness

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Appelusa Functional Health & Wellness Appelusa McGlynn, FDNP | Functional Health Coach
Root-Cause Gut to Hormone Health Strategist
Virtual

Appelusa McGlynn, FDNP | Women’s Functional Health Coach
Guiding women through
•Fertility Prep 🌱
•Peri & Menopause 🌺
Root-cause Gut to Hormone health strategist

10/22/2026

No body told me how much my liver mattered for weight loss and hormones.

COMMENT “LABS” and I’ll send you the EXACT labs I work with to check client’s liver and hormones affecting sticky weight.

And if you’re struggling with stubborn weight, mood swings, brain fog, or “estrogen dominance” symptoms… this might be the missing piece.

Here’s what I wish I knew sooner:

✨ 1. Your liver clears estrogen.
Even if your estrogen labs are “low,” if your liver isn’t clearing it efficiently, estrogen can recirculate through the gut and create dominance symptoms — bloating, heavy cycles, breast tenderness, irritability.

✨ 2. Chronic stress slows detox.
When your body is in survival mode, detox is not the priority. Cortisol comes first.
You cannot out-supplement a nervous system that feels unsafe.

✨ 3. Low protein = sluggish detox.
Phase 2 liver detox requires amino acids (glycine, taurine, glutamine, cysteine).
Under-eating or low-protein diets slow this pathway — and hormones don’t clear efficiently (that’s why I’m making bone broth! 😋)

✨ 4. Your liver activates thyroid hormone.
T4 must convert to active T3.
If the liver is sluggish, metabolism slows (em weight gain) — even if TSH looks “normal.”

✨ 5. Toxins change the equation.
Pesticides, plastics, xenoestrogens, birth control history, heavy metals — they don’t just disappear.
Metals can displace minerals.
Toxins accumulate in tissues when detox pathways are overwhelmed.

And when that happens?
→ Brain fog
→ Skin flares
→ Fatigue
→ Weight that won’t budge
→ Bloating as the day goes on

Your body isn’t broken.
It’s compensating.

This is why I always say: Test. Don’t Guess.

If you’ve been told everything looks “fine” but you don’t feel fine — that’s your sign.

Get ACTUAL DATA. CUSTOM PLAN. REAL RESULTS 👇

➡️COMMENT “LABS” and I’ll send you the EXACT labs I work with to reverse my client’s brain fog, fatigue, mood swings, bloating and skin issues.

10/15/2026

You’re eating less, cutting carbs, skipping meals, and choosing salads over satisfying meals…

But the scale isn’t moving. And somehow, you’re feeling MORE tired, bloated, and frustrated.

Here’s what many women aren’t being told about weight gain in perimenopause:

It’s not always about eating too much. Your hormones are changing how your body responds to food, stress, and metabolism.

As estrogen fluctuates and eventually declines, several things can happen:

▪️ Blood sugar regulation changes. Declining estrogen can contribute to reduced insulin sensitivity, making blood sugar management more challenging.

▪️ Muscle mass becomes harder to maintain. Losing muscle can reduce how much energy your body burns at rest.

▪️ Stress and sleep become bigger players. Poor sleep and chronic stress can influence cortisol patterns, appetite, insulin sensitivity, and where your body stores fat.

▪️ Nutrient intake may suffer. Skipping meals and overly restricting food can leave you short on protein, essential fats, vitamins, and minerals needed to support hormone production, thyroid function, and energy metabolism.

So what’s the answer?

Not necessarily eating LESS.

It’s learning how to nourish your body differently.

✔ Prioritize protein at every meal to support muscle maintenance.

✔ Include healthy fats and fiber-rich carbohydrates instead of fearing entire food groups.

✔ Support blood sugar balance with regular, balanced meals.

✔ Incorporate strength training to preserve muscle and metabolic health.

✔ Investigate underlying contributors like thyroid dysfunction, insulin resistance, poor sleep, and nutrient deficiencies when symptoms persist.

And remember: weight gain in perimenopause isn’t always JUST about estrogen.

Your gut, thyroid, blood sugar, stress physiology, and nutritional status all deserve consideration.

The goal isn’t to eat as little as possible. It’s to give your changing body what it needs to function well.

💬 Comment LABS on my Instagram for my FREE guide to the labs I use to investigate underlying contributors to stubborn weight gain, fatigue, and hormonal symptoms in women.

10/05/2026

When weight becomes harder to manage in your 40s, calories are only one part of the conversation (and many women I see aren’t actually getting enough!)

I also want to understand what’s happening with:

▪️ Hormone metabolism
▪️ Thyroid function
▪️ Blood sugar regulation
▪️ Bile flow
▪️ Digestion and nutrient absorption
▪️ Inflammation
▪️ Stress physiology
▪️ Liver function

🔔Your liver is involved in processing hormones, regulating cholesterol, storing and releasing glucose, producing bile and clearing metabolic byproducts.

That doesn’t mean every weight struggle is a “liver problem.”

It means metabolism is a system — and I want to investigate the whole system rather than blaming willpower.

✔️ Gather the data
✔️ Find the bottlenecks
✔️ Support the systems involved
✔️ Personalize the protocol

If you’re struggling with stubborn weight, hormone symptoms or metabolic changes in your 40s and want to know the EXACT functional labs I use with women to investigate what may be happening underneath, comment LABS and I’ll send you my free guide.

10/03/2026

When I’m reviewing bloodwork alongside symptoms like bloating, reflux, constipation, diarrhea, fatigue, food reactions or brain fog, these are some of the patterns that catch my attention:

1. White Blood Cells (WBC)
Your overall white blood cell count gives us a broad look at immune activity.
2. Neutrophils
These are rapid-response immune cells, particularly important in bacterial defense.
3. Lymphocytes
These include T and B cells involved in adaptive immune defense. Patterns involving lymphocytes can occur with infections and inflammation.
4. Monocytes
Think of these as part of the immune system’s clean-up crew. Inflammation, certain infections and intestinal parasites are among possible reasons for elevations
5. Eosinophils
These especially get my attention with digestive symptoms because elevations can occur with parasitic infections and allergic/atopic conditions.
6. Basophils
Basophils release histamine and participate in allergic and immune responses. When eosinophils + basophils are both elevated, parasites are one possibility I may want to investigate.
7. Neutrophil-to-Lymphocyte Ratio (NLR)
Instead of looking at immune cells in isolation, ratios can give additional context about systemic inflammatory and immune activity. Again: it’s a clue, not a gut diagnosis.
8. MCV / MCH / MCHC + iron, ferritin, B12 and folate
I look for patterns suggesting anemia or nutrient insufficiency. Then the question becomes WHY? Dietary intake? Blood loss? Increased requirements? Or could impaired digestion/absorption be contributing?
9. hs-CRP
This is a marker of systemic inflammation, not specifically gut inflammation. But if it’s elevated, I want to know what’s driving the inflammatory signal.
10. Lipid patterns
Cholesterol is deeply connected with liver and bile physiology, and metabolic inflammation can intersect with gut health.

None of these markers diagnose dysbiosis, parasites, intestinal permeability or a GI infection.

They help me identify patterns and questions worth investigating.

Want the functional ranges I use when reviewing bloodwork?

Comment RANGES and I’ll send you my free Functional Bloodwork Ranges Guide.

10/01/2026

Have you spent years trying to figure out what’s causing your bloating, fatigue, brain fog, or skin issues?

Have you been told your labs are “normal”?

Or been handed a prescription that never fixed the problem?

One area I often investigate is the health of the gut barrier. By the way- your doctor WON’T test for this!

Your intestinal lining is only a single cell layer thick. These epithelial cells create a protective barrier between the contents of your digestive tract and a large portion of your immune system.

Every day, that barrier is exposed to stress, infections, medications, environmental toxins, inflammatory foods, and microbial imbalances. Over time, these factors can contribute to increased intestinal permeability—often referred to as “leaky gut.”

The gut is complex, and there is rarely one single root cause.

That’s why functional medicine is about putting the pieces of your health puzzle together. Instead of simply managing symptoms, we investigate the factors that may be driving them and create actionable steps to help you move forward.

You deserve more than years of guessing, symptom chasing, and doom-scrolling for answers.

You deserve a plan that actually works.

📞I offer a free Discovery call. Check out the links in my bio to explore and book.
➡️ Comment LABS for my free Functional Lab Guide 📖

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Poipu, HI

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