10/31/2026
🎧 It started as a failed treatment for venous ulcers. It became one of the most influential products in professional skincare.
Mitchel P. Goldman, MD, co-founder of SkinMedica, tells the story of how TNS was created on Skincare Confidential, in conversation with Dr. Ted Lain. A passing comment from Dr. Richard Fitzpatrick about the skin around a wound led to the first growth factor serum, and Dr. Goldman explains why it was a "longevity" product decades before the term existed.
In this episode:
🌟 Why the full mix of growth factors, secretomes, and exosomes may work better than any single ingredient
🌟 How Dr. Goldman rotates growth factor products and lets patients' results guide the choice
🌟 Pre- and post-procedure skincare, and priming fibroblasts with topical rapamycin
🌟 Whether skin longevity takes multi-targeted or single-pathway products
🌟 Why he favors topicals over systemic anti-aging therapies
🌟 Why aesthetic dermatology deserves a bigger place in residency training
📍 Listen now on Apple Podcasts, Spotify, Amazon Music, iHeart Radio, or Audacy. Link in bio.
🏆 Voted #1 in San Diego & America | CLDerm.com