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Spectral Instruments Imaging Spectral Instruments Imaging (SI Imaging) came about by teaming the camera expertise of Spectral Ins He is currently CEO of Matrix Sensors.

Spectral Instruments Imaging (SI Imaging) came about by teaming the camera expertise of Spectral Instruments with the system expertise of the developers of the first high sensitivity laboratory imaging systems designed primarily for the demanding application of bioluminescent animal imaging. Spectral Instruments has for many years provided the cameras for these systems as well as for many other challenging applications. The Spectral Instruments logo is visible on thousands of cameras used in laboratories around the world. Pooling these complementary talents has resulted in the ability to design and manufacture advanced laboratory imaging systems like no others in the world. Bo Nelson, founder and Chief Technical Officer – Bo is one of the original members of the team that developed the Xenogen IVIS® systems prior to Xenogen’s acquisition by Caliper Life Sciences. For seven years, Bo was in charge of the Instrumentation department of Xenogen, where he led the team that produced, calibrated, installed, serviced and supported the entire IVIS product line and accessories. Bo has additionally worked at both Lawrence Livermore Laboratories and General Atomics, where he has become very familiar with the instrumentation needs of scientific teams. "In my time at Xenogen, we routinely used Spectral Instruments cameras in our quest to build the best system possible because SI cameras were and are simply the best. I’m thrilled to be part of the SI Imaging team and am really enjoying partnering my systems expertise with their camera expertise." Mike Cable, founder and advisor – Mike assembled and led the team that developed the Xenogen IVIS systems. As CTO of Xenogen, for six years he oversaw all aspects of the instrumentation development and manufacturing. He served as a key member of the Xenogen management team from shortly after its founding through the company’s IPO prior to its acquisition by Caliper Life Sciences. Mike has also been involved or held executive positions with several other high tech companies including Quantum Dot, Fovi Optics and Xradia. "I thought we did a fantastic job back in the 90s with the tools available then, but the SI Imaging team has surpassed those efforts in every way, using modern technologies to achieve a truly remarkable system." Keith Copeland, founder and CEO – Keith started SI Imaging with the other founders to develop and manufacture the next generation molecular imaging system. Keith has been CEO of Spectral Instruments for 17 years. Prior to that he lead the development team and then ran manufacturing at Ventana Medical Systems (Roche) for the first Immunohistochemistry instrument. He started out his career doing mechanical design on CCD cameras at Photometrics (Roper). "From a business standpoint, this is the next logical step forward for us in that we have provided for many years the key component for others to produce high quality imaging systems. Now designing and producing systems that go directly to the end user for turnkey applications is a business I’m really excited about developing and growing." Gary Sims Ph.D., founder, President - Gary has 30 years experience developing and testing solid state imaging sensors and systems for scientific measurement applications including analytical spectroscopy, astronomy, high energy physics programs, bioluminescence measurement systems, and x-ray crystallography detectors. He is an author of numerous scientific publications and patents and is President, CTO and a founder of Spectral Instruments. "We have always prided ourselves on building the best cameras possible for the most demanding applications. The challenge of taking this to the next level and providing a whole system that includes applications as difficult as bioluminescent animal imaging is something we’re eagerly embracing." IVIS® is a registered trademark of Caliper Life Sciences, Inc.

Aura 5.2 brings added capabilities and performance improvements designed to make image acquisition workflows more effici...
10/15/2026

Aura 5.2 brings added capabilities and performance improvements designed to make image acquisition workflows more efficient and reliable.

Aura 5.2 includes:
• Color image acquisition
• Improved stability, reliability, and performance
• SmartAuto Exposure options: Standard and Rapid
• Updated Acquisition Settings for a more streamlined workflow

If you haven't upgraded yet, request your Aura 5.2 upgrade today: https://ow.ly/h0QR50Zn8N9

10/13/2026

Struggling to detect small cell populations or low-expression targets, in vivo?

Our advanced in vivo imaging systems capture even the weakest signals, revealing key biological details often missed by other platforms. See what you're missing!

Explore more in our poster: https://ow.ly/FBhe50U9EKL

How can multimodal preclinical imaging help researchers gain more meaningful data while supporting better animal welfare...
10/08/2026

How can multimodal preclinical imaging help researchers gain more meaningful data while supporting better animal welfare? This new article from Technology Networks explores the role multimodal imaging can play in advancing the 3Rs, improving longitudinal study design, and extracting more information from each subject.

We’re especially pleased to see several of our own colleagues contributing their expertise to the discussion.

Read the full article: https://ow.ly/2vrB50ZUMcr

This past weekend at Purdue University's Preclinical Cancer Models Consortium meeting, our very own Lindsay Andrews shar...
10/07/2026

This past weekend at Purdue University's Preclinical Cancer Models Consortium meeting, our very own Lindsay Andrews shared valuable insights from Capitol Hill on issues impacting the future of in vivo research.

In her presentation, "Current State of In Vivo Research: Impressions from Capitol Hill," Lindsay discussed recent legislative activity, emerging policy trends, and the potential impact of proposed bills on the biomedical research community.

We are proud to have team members like Lindsay actively contributing to important conversations that help shape the future of preclinical research.

Struggling with aging in vivo imaging equipment?It’s time for an upgrade. Trade in your outdated system and get credit t...
10/06/2026

Struggling with aging in vivo imaging equipment?

It’s time for an upgrade. Trade in your outdated system and get credit toward next-generation imaging technology from Spectral Instruments Imaging, including our flagship Lago X.

Don’t miss your chance to elevate your research with higher sensitivity, faster acquisition, and unmatched reliability.

Request your quote today: https://ow.ly/CkLg50WyWR3

Building an animal model for optical imaging requires careful planning, ethical considerations, and technical expertise....
10/01/2026

Building an animal model for optical imaging requires careful planning, ethical considerations, and technical expertise.

Read our tech note - Key Considerations for Developing Animal Models for Optical Imaging — to learn more: https://ow.ly/Ylwg50StsRK

New On-Demand Webinar!Watch our latest recorded webinar "Lighting Up Immunity: Fluorescence-Based Non-Invasive Whole-Bod...
09/29/2026

New On-Demand Webinar!

Watch our latest recorded webinar "Lighting Up Immunity: Fluorescence-Based Non-Invasive Whole-Body Imaging in Acute & Chronic Murine Models of Human Diseases - A Resource Lab Perspective"

In this webinar, we explore the fundamentals of fluorescence-based non-invasive whole-body imaging and its applications in preclinical research.

We also discuss the basics of fluorescence screening, optimization, and related probe selection, as well as opportunities to incorporate fluorescent imaging into multimodal screening approaches, along with the advantages and limitations of fluorescence-based non-invasive imaging screens. In vivo and ex vivo examples from inflammatory, infectious, and other murine models of human disease will highlight the value of fluorescent modalities in whole-body imaging studies.

Watch now: https://youtu.be/c7yobfEhlRA

Have questions about in vivo imaging? We’ve got answers!Our FAQ page covers key topics spanning biological consideration...
09/24/2026

Have questions about in vivo imaging? We’ve got answers!

Our FAQ page covers key topics spanning biological considerations, system operation, and software analysis. Designed to help you get the most from your imaging workflows.

Explore the FAQs and find the guidance you need: https://ow.ly/gsNr50Y6Fca

Our patented LED fluorescence excitation method delivers powerful, reliable, & stable excitation light with a narrow ban...
09/22/2026

Our patented LED fluorescence excitation method delivers powerful, reliable, & stable excitation light with a narrow bandwidth.

Expect increased fluorescence specificity & sensitivity, while minimizing the unwanted light leakage associated with traditional white-light sources that can compromise data quality.

Learn more: https://ow.ly/yswF50ZJG51

Last chance to register!Join us tomorrow for our upcoming webinar exploring the fundamentals of fluorescence-based non-i...
09/21/2026

Last chance to register!

Join us tomorrow for our upcoming webinar exploring the fundamentals of fluorescence-based non-invasive whole-body imaging and its applications in preclinical research.

We'll discuss the basics of fluorescence screening, optimization, and related probe selection, as well as opportunities to incorporate fluorescent imaging into multimodal screening approaches, along with the advantages and limitations of fluorescence-based non-invasive imaging screens. In vivo and ex vivo examples from inflammatory, infectious, and other murine models of human disease will highlight the value of fluorescent modalities in whole-body imaging studies.

Tuesday, September 22 | 9:00 AM PDT / 12:00 PM EDT

Register here: https://ow.ly/PX5E50ZJ2gV

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