10/05/2026
Your gut bacteria may be helping decide how your brain’s immune cells behave.
Dietary fiber feeds beneficial gut bacteria, which produce compounds called short-chain fatty acids. One of them, butyrate, helps maintain the intestinal barrier and regulate inflammation, with effects that can ultimately reach microglia, the brain’s resident immune cells.
This gives us a very different way to think about fiber. What you feed your gut microbes may influence the inflammatory environment in which your brain ages.
Here’s my recent blog post on why fiber may be one of the most important nutrients for your brain: https://drperlmutter.com/fiber-may-one-important-nutrients-brain/