02/10/2026
LET’S TALK ABOUT GLP-1s.
Few health topics seem to divide people quite like weight-loss medication. They work. They also come with trade-offs. Both things can be true.
Before picking a side — and we’re not sure sides are even necessary — it’s worth understanding the strongest arguments on both. Be curious. Be as informed as you can. Be kind to yourself and to people making different choices. Most health decisions aren’t black and white.
Or, less professionally:
Don’t be kak, mos. 😂
THE CASE FOR
GLP-1–based medicines such as semaglutide, and dual GIP/GLP-1 medicines such as tirzepatide, can produce substantial weight loss. They can reduce hunger and increase fullness — and for some people, dramatically reduce the constant “food noise” that makes eating less incredibly difficult.
Their benefits can also extend beyond the number on the scale, with evidence of meaningful metabolic and cardiovascular benefits in appropriate patients. Body weight isn’t simply a reflection of discipline. Appetite and body weight are influenced by biology, genetics, environment, sleep, medication, psychology, socioeconomic circumstances and behaviour.
Read that again.
For people who medically benefit from them, medication can be a legitimate part of treatment.
THE CASE AGAINST
These aren’t consequence-free weight-loss tools. Stopping treatment commonly results in substantial weight regain, meaning that for many people this may be long-term treatment. Weight lost (in general) often isn’t exclusively fat. Lean tissue can be lost too — particularly relevant when we care about strength, ageing, bone health and physical capacity. That doesn’t make the medication bad. It means this needs to be understood and managed.
There are side effects, costs and unanswered questions about very long-term, widespread use. And importantly: Weight loss isn’t synonymous with health. Someone can become lighter without becoming stronger, fitter, better nourished or healthier.
SO WHY ARE WE ALL FIGHTING?
Maybe because weight sits at the intersection of health, appearance, identity, discipline, biology, culture and morality — and we’ve become very good at turning complicated questions into teams.
Taking