04/11/2026
🚨 Could a blood test help spot several ABDOMINAL cancers earlier? 🩸
As a GP and bowel cancer survivor, I’m VERY interested in this trial, especially when symptoms are vague. Early diagnosis is crucial.
In England each year:
❌Around 71,000 people are diagnosed with bowel, ovarian, pancreatic, stomach or liver cancer.
❌These cancers cause almost 35,000 deaths.
❌Only around ONE IN FOUR pancreatic and stomach cancers are diagnosed early.
The government funded STRIDE-RCT will involve over 20,000 NHS patients across at least 200 GP practices in England.
🔎 WHO IS IT FOR?
People aged 45+ with abdominal symptoms such as persistent bloating, discomfort or bowel changes. These often have other causes, but may need investigation.
🧬 HOW DO THE TESTS WORK?
Different approaches look for:
• Tumour DNA: fragments shed by cancer cells, with chemical marks that may suggest where cancer started.
• Blood proteins: patterns associated with cancer and the body’s response.
• AI: patterns in blood results alongside information such as age and s*x.
🩸 WHAT HAPPENS?
Most tests need one or two tubes of blood alongside routine tests, with results expected within days.
❓WHICH CANCERS?
Bowel, small bowel, stomach, oesophageal, pancreatic, liver, bile duct, gallbladder, ovarian, endometrial, kidney, bladder and prostate.
⚠️ WHAT DO RESULTS MEAN?
• A positive signal does NOT confirm cancer. Further tests are needed; results may guide where to investigate.
• No signal does NOT rule cancer out. Persistent or worsening symptoms need follow-up.
📋 WHY A TRIAL?
To establish whether testing helps GPs diagnose cancer earlier and reduce unnecessary urgent referrals alongside clinical judgement.
Practices are randomly allocated to testing plus usual care or usual care for comparison.
📅 WHEN?
Testing is expected from April 2027. This is a government-funded trial, not a national rollout.
🔴 Don’t wait for a future test if you have symptoms, whatever your age. Go back if symptoms persist or worsen.
Questions / comments welcome ⬇️