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Functional Medicine CE Quality functional medicine CE without travel! Live and on-demand CE available.

The mycotoxin results are back. Now what?How do you decide which findings matter, what to address first, and how to buil...
30/10/2026

The mycotoxin results are back. Now what?

How do you decide which findings matter, what to address first, and how to build an individualized clinical protocol?

Join Dr. Kristi Hughes for a FREE live webinar as she walks through real patient cases, from test interpretation and clinical decision-making to protocols and patient outcomes.

> Thursday, November 5 | 1 PM ET
> Free live webinar | Sponsored by KBMO

Comment MYCOTOXIN for the link or find the link in our bio!

29/10/2026

Same diagnosis. Same PHQ-9. Same SSRI.

Six weeks later, one patient feels like herself again. The other is back in your office asking what’s next.

So what was different? Often, it’s something that never made it into the workup:
* Sleep disruption
* Thyroid, anemia, or nutrient deficiencies
* Poorly controlled blood sugar
* A medication that’s affecting mood
* The gut microbiome

When a patient isn’t responding after the second or third antidepressant, it’s time to look wider, not just reach for the next prescription.

That’s exactly what we cover in Functional and Integrative Approaches to Mood, Anxiety, and Attention Disorders, a 14-hour CE/CME program for pharmacists, physicians, NPs, PAs, and dietitians who want more tools for these patients.

Comment MENTAL HEALTH and I’ll send you the details on how to register. (Free preview tomorrow!)

27/10/2026

When a patient tells you their anxiety seems to come out of nowhere, do you ask when they last ate?

Blood sugar fluctuations can produce physical symptoms that overlap with anxiety, including shakiness, irritability, lightheadedness, and a racing heart.

And for some patients, meal timing and what they’re eating may be contributing to those symptoms.

In this clip from the Table Talk Podcast, Everest Goldstein, a Board-Certified Psychiatric Nurse Practitioner also certified in Functional Medicine, joins Melody Hartzler, PharmD, to discuss the relationship between blood sugar regulation and anxiety, including why pairing carbohydrates with protein, fat, and fiber may help.

It’s one example of why a thorough mental health assessment should consider metabolic health alongside psychological and psychiatric factors.

We’re excited to welcome Everest as a faculty member for our upcoming Mental Health Summit: Functional and Integrative Approaches to Mood, Anxiety, and Attention Disorders.

Join us for our FREE live kickoff on October 30 at 3 PM ET, where we’ll explore physiologic contributors that deserve consideration in mental health care.

When a patient with depression or anxiety isn’t improving, what else deserves a closer look?Medication effects, nutrient...
26/10/2026

When a patient with depression or anxiety isn’t improving, what else deserves a closer look?

Medication effects, nutrient deficiencies, metabolic dysfunction, hormonal changes, and sleep disruption can all influence how a patient feels and, in some cases, how they respond to treatment.

We’re also learning more about the roles of inflammatory signaling, gut–brain interactions, and pharmacogenomics in mental health.

But here’s where clinical reasoning becomes especially important: Not every potential contributor is relevant to every patient. And not every abnormal finding requires intervention.

The goal is to recognize when a more comprehensive assessment is warranted, understand which findings are meaningful, and use that information to make better clinical decisions.

That’s what we’re exploring in our upcoming Mental Health Summit: Functional and Integrative Approaches to Mood, Anxiety, and Attention Disorders.

We’re kicking things off with a FREE live session led by Melody Hartzler, PharmD:
Mental Health in Clinical Practice: The Gap, the Physiology, and the Path Forward
Friday, October 30 | 3 PM ET

We’ll explore where current approaches to mental health care may leave unanswered questions and how clinicians can evaluate additional physiologic contributors while keeping evidence-based treatment and patient safety at the center.

Mental health care is becoming increasingly complex. And for patients who aren’t responding as expected to treatment, th...
23/10/2026

Mental health care is becoming increasingly complex. And for patients who aren’t responding as expected to treatment, there’s often more to investigate.

How might inflammation, metabolic dysfunction, nutrient status, hormonal changes, sleep, or medication effects be contributing to their symptoms? And how can we use that information to make more informed treatment decisions?

That’s what we’re exploring in our upcoming Mental Health Summit: Functional & Integrative Approaches to Mood, Anxiety, and Attention Disorders.

We’ve brought together 8 expert faculty for 14 hours of CE/CME education, covering the physiology, research, and clinical applications of integrative mental health care.

We’ll explore everything from biochemical contributors to depression and anxiety to ADHD, pharmacogenomics, medication management, and practical patient assessment.

>>> Start with our FREE live kickoff on Friday, October 30 at 3 PM ET, where Melody Hartzler, PharmD, will discuss gaps in current mental health care and opportunities for a more comprehensive clinical assessment.

Whether you’re a pharmacist, physician, NP, PA, or other healthcare professional, we’d love to have you join us.

22/10/2026

When a patient with anxiety or depression also has IBS, chronic constipation, metabolic dysfunction, or a highly restrictive diet, should we be thinking more about the gut-brain connection?

We know the gut and brain communicate through multiple pathways, including the vagus nerve, immune signaling, the HPA axis, and microbial metabolites. And emerging research suggests the relationship between the gut microbiome and mental health may be more complex than simply reducing inflammation.

One small randomized pilot study in patients with major depressive disorder found associations between changes in gut microbial composition and improvements in anxiety symptoms when a multi-strain probiotic was added to antidepressant treatment.

There’s still a great deal we need to understand about how these findings translate into clinical practice. But the research raises important questions about how we evaluate patients with persistent mental health symptoms, particularly when gastrointestinal and metabolic concerns are also present.

We’re exploring these relationships and much more during our upcoming Mental Health Summit: Functional and Integrative Approaches to Mood, Anxiety, and Attention Disorders.

Join us for our FREE live kickoff on October 30 at 3 PM ET.

Already an Annual Pass member? Your summit access is included, and we’ll see you in November!

For many patients, that means continuing to struggle with fatigue, low motivation, brain fog, or anxiety, even after sta...
21/10/2026

For many patients, that means continuing to struggle with fatigue, low motivation, brain fog, or anxiety, even after starting treatment.

And when the first medication doesn’t work, what comes next?

A dose adjustment? A different antidepressant? An additional medication?

Those may be appropriate next steps. But it’s also worth considering what else could be contributing to their symptoms.

Medication-related adverse effects, nutrient deficiencies, metabolic dysfunction, inflammation, hormonal changes, and disrupted sleep can all be relevant to the clinical picture.

The challenge is knowing what to evaluate, which findings actually matter, and how to use that information to guide treatment.

That’s why we created our upcoming Mental Health Summit: Functional and Integrative Approaches to Mood, Anxiety, and Attention Disorders.

We’re kicking things off with a FREE live session led by Melody Hartzler, PharmD:
Mental Health in Clinical Practice: The Gap, the Physiology, and the Path Forward

> Friday, October 30 | 3 PM ET

We’ll explore current treatment-response data, potential physiologic contributors to psychiatric symptoms, and how clinicians can approach these complex cases with a more comprehensive clinical framework.

21/10/2026

Depression and anxiety are among the most common concerns clinicians encounter.

But what happens when first-line treatment isn’t getting patients where we want them to be?

What else should we be looking at?

Inflammation, nutrient status, metabolic health, hormones, circadian rhythm, and even medications themselves can all influence mood, anxiety, and cognitive symptoms.

On Friday, October 30, Dr. Melody Hartzler is kicking off our Mental Health Summit with a FREE live session:
> Mental Health in Clinical Practice: The Gap, the Physiology, and the Path Forward

We’ll look at where conventional treatment approaches can fall short, the physiologic contributors worth investigating, and how clinicians can begin building a more comprehensive approach to mental health care.

> Friday, October 30 | 3–4 PM ET
> Live on Zoom | FREE to attend
> Open to pharmacists, physicians, NPs, PAs, and other healthcare professionals

Join us for the kickoff!

Remember learning that the innate immune system responds quickly but doesn’t have memory?Research on trained immunity ha...
15/10/2026

Remember learning that the innate immune system responds quickly but doesn’t have memory?

Research on trained immunity has challenged that traditional understanding.

Certain innate immune cells can undergo epigenetic and metabolic changes following an immune challenge, influencing how they respond to future exposures.
And that matters when we’re thinking about chronic inflammation.

The innate immune system does more than provide an immediate defense. It also helps shape adaptive immune responses and may play an important role in the development and persistence of immune-mediated inflammatory conditions.

In our latest 1-hour CE/CME course (and last 1-hr session of 2026!), Fundamentals of Autoimmune & Autoinflammatory Conditions, Dr. Thomas Guilliams explores trained immunity, Toll-like receptors, the NLRP3 inflammasome, and how these mechanisms relate to chronic inflammatory disease.

We know the gut microbiome influences far more than digestion. But an increase in beneficial bacteria doesn’t necessaril...
13/10/2026

We know the gut microbiome influences far more than digestion. But an increase in beneficial bacteria doesn’t necessarily mean we’re seeing an improvement in gut health.

A 2026 review in Gut Microbes Reports explores how dietary interventions influence both microbial composition and function, including short-chain fatty acid production, bile acid metabolism, and other microbial processes involved in human health.

One interesting point the authors raise is that changes in microbial composition don’t always tell us how the microbiome is functioning or how a patient will respond to a dietary intervention.

For clinicians, this highlights the importance of interpreting microbiome findings alongside the patient’s symptoms, dietary patterns, medications, and overall clinical picture.

As research advances, we’re learning more about how microbial activity influences health and how that information might help guide more individualized nutrition and treatment decisions.

Knowing which microbes are present is valuable. Understanding what they’re doing adds another layer to the clinical picture.

Source: Day AS, et al. Gut Microbes Reports. 2026.
https://doi.org/10.1080/29933935.2026.2744027

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