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Monday 09:00 - 16:00 Tuesday 09:00 - 17:00 Wednesday 09:00 - 16:00 Thursday 09:00 - 16:00 Friday 09:00 - 16:00

Tiervlei Trial Centre

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Tiervlei Trial Centre

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Tiervlei Trial Centre is a well-established clinical research centre based in Cape Town.

Tiervlei Trial Centre is a well established centre, specialising in the conduct of national and international clinical trials. TTC has successfully participated in more than 200 clinical trials within the following therapeutic areas: Respiratory, Cardiovascular, Neurology, Metabolic, Phytotherapies, Infectious Disease, Bioequivalence and Phase I. We provide specialised services from the conduct of clinical trials to medical writing, data management and biometry and have completed more than 15 Clinical Study Reports for registration of new medicines.

10/11/2026

Tiervlei Trial Centre (TTC) is a well-established private clinical trial centre. We specialise in the conduct of national and international clinical research. Contact us if you are interested in participating in clinical research.

7th Floor, The View, Tygervalley Health Centre, 43 Old Oak Road, Bellville, 7530 | Office Number: 021 957 9400 | E-mail: [email protected] | Website: www.ttc-trials.co.za

05/11/2026

Meet Marius Engelbrecht | Data Scientist and General Manager at Tiervlei Trial Centre 📊

Marius Engelbrecht is a qualified scientist with a passion for data-driven decision-making, operational excellence and advancing clinical research through the smart use of technology.

With a strong foundation in genetics and molecular biology, he has spent the past two years applying an analytical, data-centric approach to clinical and medical research operations. As Data Scientist and General Manager, Marius leads TTC’s data science and general management functions, overseeing CRIO implementation, IT infrastructure, information systems and automated dashboards that provide clear visibility into the Centre’s day-to-day operations.

Marius completed his BSc in Molecular Biology and Biotechnology, BScHons in Human Genetics and MSc in Human Genetics at Stellenbosch University. He progressed through Data Scientist and Business Support and Information Manager roles at TTC before moving into his current leadership position. His background in high-throughput bioinformatics brings a rigorous, methodical approach to operational data, KPI reporting and process optimisation.

In a research environment that increasingly relies on accurate, real-time data,
Marius is committed to ensuring that operational insight goes hand in hand with quality, compliance and organisational efficiency.

We are proud to have him as part of TTC’s leadership team, helping to build a research environment that is data-driven, technology-enabled and focused on operational excellence.

Research. Innovation. Quality. Better healthcare.

03/11/2026

Looking for Adults with MASH to Participate in a Research Study.

The ENLIGHTEN Fibrosis research study is testing an investigational study medication, called pegozafermin, for adults with MASH.

Are you overweight? Do you also have any of the following?
High blood pressure, high triglycerides, high blood sugar, or high cholesterol.
If yes, you may have MASH (previously known as NASH, or non-alcoholic steatohepatitis).

Learn about MASH and find out if you qualify for the ENLIGHTEN Fibrosis research study.

What is MASH?
MASH stands for metabolic dysfunction-associated steatohepatitis. It is a liver disorder, linked to metabolic issues, that causes fat to build up within the liver. Fat buildup leads to inflammation and ultimately scarring of the liver.
MASH often does not have symptoms, but over time, the scarring can become advanced, resulting in cirrhosis and even liver failure.

Why join the ENLIGHTEN Fibrosis study?
Study participants receive the following:
• Testing to find out if you have MASH and which research study may be best for you
• Possible access to the investigational study medication — 2 in 3 participants will receive active study medication; 1 in 3 participants will receive placebo, which has no active ingredients
• Study support and monitoring by a healthcare team
• The opportunity to help advance MASH research

Talk to an ENLIGHTEN Fibrosis study team member today.

Tiervlei Trial Centre, 7th Floor, The View, Tygervalley Health Centre, 43 Old Oak Road, Bellville, 7530 | Office Number: 021 957 9400 | E-mail: [email protected] | Website: www.ttc-trials.co.za

29/10/2026

🚨 Know the signs.

Did you know that approximately 1 in 4 adults worldwide will experience a stroke during their lifetime?

A stroke occurs when blood flow to part of the brain is blocked or a blood vessel in the brain bursts. Brain cells can begin to die within minutes, making quick action essential.

Recognising the warning signs could save a life!

Remember FAST:

🔹 F – Face: Is one side of the face drooping?

🔹 A – Arms: Is one arm weak or numb? Can the person raise both arms?

🔹 S – Speech: Is their speech slurred or difficult to understand?

🔹 T – Time: Call emergency services immediately!

Other warning signs include sudden confusion, vision problems, dizziness, loss of balance or a severe headache with no known cause.

💙 Prevention matters, too!

Managing your blood pressure, staying active, eating a balanced diet, avoiding smoking and keeping conditions such as diabetes and high cholesterol under control can help reduce your stroke risk.

At Tiervlei Trial Centre, we believe that awareness, early intervention and continued medical research all play an important role in improving healthcare outcomes.

⏱️ Every minute counts. If you recognise the signs of a stroke, don't wait. Call for emergency medical help immediately.

Share this post. You never know whose life it could help save.

27/10/2026

Are you experiencing any of the following symptoms?

🔹 A persistent cough
🔹 Sputum (phlegm)
🔹 Shortness of breath

These could be signs of Chronic Obstructive Pulmonary Disease (COPD), a long-term lung condition that affects breathing.

Have you been diagnosed with COPD?

Tiervlei Trial Centre (TTC) is conducting clinical trials focused on pulmonary diseases, including COPD, to help advance research into new and improved treatment options.

You could help advance respiratory healthcare!

If you have been diagnosed with COPD or are experiencing the symptoms mentioned above, contact our team to learn more about our pulmonary disease trials and find out whether you may qualify.

22/10/2026

Meet Dr Haylene Nell | Co-founder and Executive Head at Tiervlei Trial Centre 🔬

With nearly four decades of clinical research experience, Dr Nell has contributed to more than 500 clinical trials and served as Principal Investigator on approximately 150 studies. Her expertise spans clinical pharmacology, respiratory medicine, medicines development, and the design and delivery of high-quality clinical trials.

Since co-founding Tiervlei Trial Centre in 2000, Dr Nell has played a central role in developing TTC into an established clinical research site. She provides strategic and scientific leadership, supports investigator development, and helps ensure that research is conducted with scientific rigour, operational excellence, and the highest regard for participant safety.

Dr Nell is particularly passionate about advancing medicines through ethical, high-quality research and developing the next generation of clinical research professionals. Her career reflects a longstanding commitment to research that is scientifically meaningful, professionally respected, and capable of contributing to better patient care.

We are proud to have Dr Haylene Nell as part of the TTC leadership team and to benefit from the depth of knowledge, experience, and commitment she brings to clinical research.

Leadership. Experience. Scientific excellence. Better healthcare.

20/10/2026

Do you smoke or have you smoked before?

Do you experience a persistent cough, sputum (phlegm), or shortness of breath? You may have COPD (Chronic Obstructive Pulmonary Disease).

Tiervlei Trial Centre is currently running clinical trials to help develop new COPD medicines.

Interested? Contact us to learn more:
📞 Phone: 021 957 9400
📱 WhatsApp: 079 578 4731

Eligibility criteria will apply.

15/10/2026

October is Breast Cancer Awareness Month and we are looking back to one of our Breast Cancer Awareness campaigns, working in collaboration with the Durbanville Clinic and Reach for Recovery (Tygerberg) to raise awareness

Here are some key facts about Breast Cancer from the World Health Organisation

💟 Breast cancer caused 670,000 deaths globally in 2022.
💟 Roughly half of all breast cancers occur in women with no specific risk factors other than s*x and age.
💟 Breast cancer was the most common cancer in women in 157 countries out of 185 in 2022.
💟 Breast cancer occurs in every country in the world.
💟 Approximately 0.5–1% of breast cancers occur in men.

08/10/2026

Meet Dr Marlene Nell | Clinical Research Manager at Tiervlei Trial Centre 🔬

Dr Marlene Nell is a medical doctor with a passion for evidence-based medicine, quality research and advancing healthcare.

With five years of clinical trial experience as an investigator, she has contributed to studies across various therapeutic areas, including respiratory, cardiovascular, infectious diseases and paediatrics. As Clinical Research Manager, she now brings her first-hand investigator experience into a leadership role, focusing on quality management, operational excellence and the responsible integration of modern technologies into clinical research.

Dr Nell completed her medical degree at Stellenbosch University in 2016 and has since worked across various healthcare settings in South Africa before returning to Cape Town. Her background in general practice, emergency medicine and rehabilitation adds valuable clinical perspective to her research expertise.

In an evolving clinical trial landscape, Dr Nell is committed to ensuring that innovation goes hand in hand with quality, integrity, regulatory compliance and participant safety.

We are proud to have her leading and contributing to a research environment that is quality-driven, technology-enabled and focused on better healthcare outcomes.

Research. Innovation. Quality. Better healthcare.

Address

7th Floor, Tygervalley Health Care Centre, 43 Old Oak Road, Tygervalley
Cape Town
7530

Opening Hours

Monday	09:00 - 16:00
Tuesday	09:00 - 17:00
Wednesday	09:00 - 16:00
Thursday	09:00 - 16:00
Friday	09:00 - 16:00

Telephone

+27219579400

Website

http://www.ttctrials.co.za/

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