11/02/2026
For 70 years, living with CAH (Congenital Adrenal Hyperplasia) has meant one main tool:
Steroids. Often high doses, taken for life, with side effects that pile up over time.
That changed recently.
At ENDO 2026, Dr. Richard Auchus of the University of Michigan explained how Crenessity (crinecerfont), the first drug of its kind for CAH, works on the problem from a different angle. Instead of only replacing what the body can’t make, it calms the signal that pushes the adrenal glands into overdrive. The payoff is that many people can manage their CAH on lower steroid doses.
Lower doses can mean better bone health, easier weight management, and better insulin sensitivity.
One important note: this medication works alongside steroid treatment, not instead of it. **Never change your dose without your endocrinologist.**
Watch the full interview: https://vist.ly/5q29i
We welcome Dr. Richard Auchus as he discusses congenital adrenal hyperplasia (CAH), its current treatments, and introduces a groundbreaking drug, Crenessity (crinecerfont), that could revolutionize management of the condition.